CD79b antibody (PE)

Catalog No. ABIN135372

Product Details anti-CD79b Antibody (PE)

Target: CD79b (CD79B) (CD79b Molecule, Immunoglobulin-Associated beta (CD79B))

Reactivity: Mouse

Host: Hamster

Clonality: Monoclonal

Conjugate: This CD79b antibody is conjugated to PE

Application: Flow Cytometry (FACS)

Specificity: Mouse CD79b, Mr 37-39 kDa

Characteristics: Hamster Anti-Mouse CD79b-PE

Purification: Ion exchange column

Immunogen: CD79alpha/CD79beta heterodimers purified from mouse (BALB/c x NZB)F1 B cell lymphoma cells, WEHI231

Clone: HM79-12

Isotype: IgG

Application Details

Application Notes:

• Applications: FC - Quality tested , IP - Reported in literature , WB - Reported in literature
• Working Dilutions: Flow Cytometry Purified (UNLB) antibody 1 g/106 cells FITC and BIOT conjugates 1 g/106 cells PE conjugate 0.2 g/106 cells For flow cytometry, the suggested use of these reagents is in a final volume of 100 L

Sample Volume: 1 mL

Restrictions: For Research Use only

Handling

Concentration: 0.1 mg/mL

Buffer: 0.1 mg in 1.0 mL of PBS/Sodium azide and a stabilizing agent

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Do not freeze!
Protect conjugated products from light.
Each reagent is stable for the period shown on the bottle label if stored as directed.

Storage: 4 °C

Storage Comment: Store at 2-8°C

Target Details for CD79b

Target: CD79b (CD79B) (CD79b Molecule, Immunoglobulin-Associated beta (CD79B))

Alternative Name: CD79b (CD79B Products)

Synonyms: B29 antibody, Ig-beta antibody, Igb antibody, Igbeta antibody, AGM6 antibody, IGB antibody, CD79B antigen antibody, CD79b molecule antibody, Cd79b antibody, CD79B antibody

Background: Murine CD79 is a 23/21 kDa disulfide-linked heterodimer composed of an chain (CD79a/mb-1) and a chain (CD79b/B29) that associates non-covalently with membrane immunoglobulin (Ig) to form the B cell receptor (BCR) complex. Its expression is restricted to B lymphocytes, first appearing on the surface at the pro-B cell stage prior to productive Ig gene rearrangements and remaining through all stages of B-cell differentiation prior to plasma cells. It has been proposed that the CD79 complex on pro-B cell surfaces may function to induce early B-cell differentiation.

Pathways: BCR Signaling