CD45RC antibody

Catalog No. ABIN135361

Product Details anti-CD45RC Antibody

Target: CD45RC

Reactivity: Mouse

Host: Rat

Clonality: Monoclonal

Conjugate: This CD45RC antibody is un-conjugated

Application: Flow Cytometry (FACS)

Specificity: Mouse CD45RC, Mr 200-240 kDa

Characteristics: Rat Anti-Mouse CD45RC-UNLB

Purification: Purified

Immunogen: Unknown

Clone: C455-1F

Isotype: IgG2a

Application Details

Application Notes:

• Applications: FC - Quality tested
• Working Dilutions: Flow Cytometry FITC and BIOT conjugates 1 g/106 cells PE conjugate 0.2 g/106 cells For flow cytometry, the suggested use of these reagents is in a final volume of 100 L

Sample Volume: 1 mL

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: 0.5 mg of purified immunoglobulin in 1.0 mL of borate buffered saline,  pH 8.2. No preservatives or amine-containing buffer salts added

Preservative: Without preservative

Handling Advice: Each reagent is stable for the period shown on the bottle label if stored as directed.

Storage: 4 °C

Storage Comment: Store at 2-8°C

Target Details for CD45RC

Target: CD45RC

Alternative Name: CD45RC (CD45RC Products)

Synonyms: CD45 antibody, L-CA antibody, Lca antibody, RT7 antibody, T200 antibody, protein tyrosine phosphatase, receptor type, C antibody, Ptprc antibody

Background: The CD45 family of cell-surface glycoprotein antigens exist as a set of isoforms. The patterns of monoclonal antibody recognition of the CD45 phenotypes can be restricted (CD45RA, RB and RC), or broader, such as the CD45 T-200 species. The restricted subsets of this group arise as a result of translation of alternatively spliced mRNAs from exons A, B and C (exons 4, 5 and 6), where exons 3-15 encode the extracellular domain of the CD45 molecule. The restricted epitopes are differentially expressed on T and B lymphocytes, including functionally distinct T cells.