CD28 antibody
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- Target See all CD28 Antibodies
- CD28
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Reactivity
- Mouse
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Host
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Hamster
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Clonality
- Monoclonal
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Conjugate
- This CD28 antibody is un-conjugated
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Application
- Flow Cytometry (FACS)
- Specificity
- Mouse CD28, Mr 40 kDa
- Characteristics
- Hamster Anti-Mouse CD28-UNLB
- Purification
- Purified
- Immunogen
- C57BL/6N mouse T cell lymphoma EL-4 cell line
- Clone
- 37-51
- Isotype
- IgG
- Top Product
- Discover our top product CD28 Primary Antibody
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- Application Notes
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- Applications: FC - Quality tested , IP - Reported in literature , Costim - Reported in literature , Stim - Reported in literature , Activ - Reported in literature , Block - Reported in literature
- Working Dilutions: Flow Cytometry FITC and BIOT conjugates 2 g/106 cells PE, APC, and SPRD conjugates 0.2 g/106 cells For flow cytometry, the suggested use of these reagents is in a final volume of 100 L
- Comment
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In vitro costimulation of T cells and NK cells
- Sample Volume
- 1 mL
- Restrictions
- For Research Use only
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- Concentration
- 0.5 mg/mL
- Buffer
- 0.5 mg of purified immunoglobulin in 1.0 mL of borate buffered saline, pH 8.2. No preservatives or amine-containing buffer salts added
- Preservative
- Without preservative
- Handling Advice
- Each reagent is stable for the period shown on the bottle label if stored as directed.
- Storage
- 4 °C
- Storage Comment
- Store at 2-8°C
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NLRP3 inflammasome in fibroblasts links tissue damage with inflammation in breast cancer progression and metastasis." in: Nature communications, Vol. 10, Issue 1, pp. 4375, (2020) (PubMed).
: "
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NLRP3 inflammasome in fibroblasts links tissue damage with inflammation in breast cancer progression and metastasis." in: Nature communications, Vol. 10, Issue 1, pp. 4375, (2020) (PubMed).
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- Target
- CD28
- Alternative Name
- CD28 (CD28 Products)
- Background
- CD28 is a type I disulfide-linked homodimer that is constitutively expressed on most thymocytes, at low density on nearly all CD4+ and CD8+ peripheral T lymphocytes, and at very low levels on NK cells. Its expression is upregulated upon T-cell activation. CD28 is a ligand for CD80/B7-1 and CD86/B7-2 on B cells and other antigen presenting cells, and plays an important role in the interaction between T cells and B cells. CD28 is a co-stimulatory receptor involved in many, but not all, T-cell independent immune responses.
- Pathways
- TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response
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