CD2 antibody

Catalog No. ABIN135080

Product Details anti-CD2 Antibody

Target: CD2

Reactivity: Mouse

Host: Rat

Clonality: Monoclonal

Conjugate: This CD2 antibody is un-conjugated

Application: Flow Cytometry (FACS), Immunoprecipitation (IP)

Specificity: Mouse CD2, Mr 45-58 kDa

Characteristics: Rat Anti-Mouse CD2-UNLB

Purification: Purified

Immunogen: Crude plasma membranes of ESb cells

Clone: 12-15

Isotype: IgG1

Application Details

Comment:

In vitro inhibition of CTL-mediated lysis, Induction of T cell unresponsiveness in vivo

Sample Volume: 1 mL

Restrictions: For Research Use only

Handling

Buffer: Product is supplied as 0.5 mg of purified immunoglobulin in 1.0 mL of 100 mM borate buffered saline, pH 8.0.

Handling Advice: Each reagent is stable for the period shown on the bottle label if stored as directed.

Storage: 4 °C

Target Details for CD2

Target: CD2

Alternative Name: CD2 (CD2 Products)

Background: CD2, also known as leukocyte function-associated antigen-2 (LFA-2), is a member of the immunoglobulin superfamily of cell adhesion molecules. It is expressed on the surface of > 95 % of thymocytes, and essentially all B cells, T cells and NK cells. In the mouse, CD2 is the receptor for CD48. CD2 is thought to play a major role in mediating T-cell adhesion, T-cell recognition/activation, T-cell signaling and intrathymic differentiation.5