Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@antibodies-online.com

CCDC98 antibody (AA 1-313)

FAM175A Reactivity: Human WB, IP, FACS Host: Mouse Monoclonal ABRA1-01 unconjugated
Catalog No. ABIN1302443
  • Target See all CCDC98 (FAM175A) Antibodies
    CCDC98 (FAM175A) (Family with Sequence Similarity 175, Member A (FAM175A))
    Binding Specificity
    • 15
    • 6
    • 4
    • 3
    • 2
    • 2
    • 1
    AA 1-313
    Reactivity
    • 24
    • 19
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 37
    • 3
    Mouse
    Clonality
    • 37
    • 3
    Monoclonal
    Conjugate
    • 17
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CCDC98 antibody is un-conjugated
    Application
    • 31
    • 13
    • 13
    • 12
    • 11
    • 9
    • 6
    • 3
    • 3
    • 3
    • 1
    • 1
    Western Blotting (WB), Immunoprecipitation (IP), Flow Cytometry (FACS)
    Specificity
    The mouse monoclonal antibody ABRA1-01 recognizes human ABRA1 (Abraxas, CCDC98), an adaptor protein involved in DNA repair, which migrates as a 45 kDa band on PAAGE under reducing conditions.
    Cross-Reactivity (Details)
    Human, Other not tested
    Purification
    Purified by protein-A affinity chromatography.
    Purity
    > 95 % (by SDS-PAGE)
    Immunogen
    Recombinant protein corresponding to amino acids 1-313 of ABRA1 with N-terminal His6 tag
    Clone
    ABRA1-01
    Isotype
    IgG
    Top Product
    Discover our top product FAM175A Primary Antibody
  • Application Notes
    Flow cytometry: Recommended dilution: 1-2 μg/mL. Intracellular staining.
    Western blotting: Reducing conditions.
    Restrictions
    For Research Use only
  • Concentration
    1 mg/mL
    Buffer
    Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Do not freeze.
    Storage
    4 °C
    Storage Comment
    Store at 2-8°C. Do not freeze.
  • Target
    CCDC98 (FAM175A) (Family with Sequence Similarity 175, Member A (FAM175A))
    Alternative Name
    ABRA1 (FAM175A Products)
    Synonyms
    CCDC98 antibody, abra1 antibody, ccdc98 antibody, fam175a antibody, ABRA1 antibody, 3830405G04Rik antibody, 5630400M01Rik antibody, AI506069 antibody, AL024423 antibody, AV118690 antibody, Ccdc98 antibody, RGD1305287 antibody, zgc:103522 antibody, abraxas 1, BRCA1 A complex subunit antibody, Coiled-coil domain-containing protein 98 antibody, BRCA1 A complex subunit antibody, family with sequence similarity 175 member A antibody, abraxas 2a, BRISC complex subunit antibody, abraxas 1, BRCA1 A complex subunit S homeolog antibody, ABRAXAS1 antibody, abraxas1 antibody, Abraxas1 antibody, FAM175A antibody, abraxas2a antibody, abraxas1.S antibody
    Background
    Abraxas 1, BRCA1 A complex subunit,ABRA1 (Abraxas), also known as CCDC98, is an adaptor protein that is essential for formation and function of BRCA1 A tumor suppressor complex. This complex plays critical roles in DNA repair, cell cycle checkpoint control, and maintenance of genomic stability. ABRA1 mediates interaction of ubiquitin-interacting motif-containing protein RAP80 and deubiquitination enzyme BRCC36 with BRCA1/BARD1. ABRA1 controls both DNA-damage-induced formation of BRCA1 foci and BRCA1-dependent G2/M checkpoint activation.,ABRA1, Abraxas 1, CCDC98, FAM175A
    Gene ID
    84142
    UniProt
    Q6UWZ7
    Pathways
    DNA Damage Repair, Positive Regulation of Response to DNA Damage Stimulus
You are here:
Support