CD58 antibody

Catalog No. ABIN94193

Product Details anti-CD58 Antibody

Target: CD58

Reactivity: Human, Pig

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD58 antibody is un-conjugated

Application: Flow Cytometry (FACS)

Specificity: The antibody MEM-63 reacts with CD58 (LFA-3), a 40-70 kDa extracellular membrane glycoprotein distributed over many tissues, leukocytes, erythrocytes, endothelial cells, epithelial cells and fibroblasts.

Purification: Purified by protein-A affinity chromatography.

Purity: > 95 % (by SDS-PAGE)

Immunogen: NALM-6 human pre-B cell line

Clone: MEM-63

Isotype: IgG1

Application Details

Application Notes: Flow cytometry: Recommended dilution: 1-4 μg/mL. Cold-induced transient opalescent turbidity may appear during the storage at 2 - 8 °C. Bring the antibody to room temperature until the turbidity disappears, and mix well before the use.

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 8.8, 15 mM sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store at 2-8°C. Do not freeze.

Target Details for CD58

Target: CD58

Alternative Name: CD58 (CD58 Products)

Synonyms: LFA-3 antibody, LFA3 antibody, ag3 antibody, CD58 molecule antibody, CD58 antibody

Background: CD58 Molecule,CD58 (LFA-3) is an immunoglobulin family adhession molecule expressed by both hematopoietic and non-hematopoietic cells (often on antigen presenting cells) and serving as ligand of CD2. This interaction is important for T cell-mediated immunity. CD58 is expressed in transmembrane form and in GPI-anchored form, the later is constitutively associated with protein kinases whereas the transmembrane form activates kinase activity upon triggering. CD58 is a powerful tool for detection of minimal residual disease in acute lymphocytic leukemia, and for evaluation of liver damage related with hepatitis B.,LFA3, AG3

Gene ID: 965

UniProt: P19256