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PCNA antibody (Internal Region)

PCNA Reactivity: Human WB, ELISA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN129712
  • Target See all PCNA Antibodies
    PCNA (Proliferating Cell Nuclear Antigen (PCNA))
    Binding Specificity
    • 16
    • 16
    • 16
    • 15
    • 12
    • 11
    • 8
    • 5
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region
    Reactivity
    • 207
    • 150
    • 149
    • 54
    • 28
    • 27
    • 21
    • 19
    • 19
    • 18
    • 17
    • 14
    • 11
    • 10
    • 6
    • 6
    • 5
    • 5
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 129
    • 91
    • 3
    Rabbit
    Clonality
    • 128
    • 94
    • 1
    Polyclonal
    Conjugate
    • 109
    • 16
    • 13
    • 8
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PCNA antibody is un-conjugated
    Application
    • 188
    • 68
    • 63
    • 59
    • 52
    • 47
    • 47
    • 40
    • 29
    • 15
    • 15
    • 11
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA
    Cross-Reactivity
    Monkey, Dog (Canine), Mouse (Murine), Rat (Rattus), Sheep (Ovine), Chicken, Fish, Xenopus laevis
    Characteristics
    Concentration Definition: by UV absorbance at 280 nm
    Immunogen
    This affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to an of human PCNA protein.
    Isotype
    IgG
    Top Product
    Discover our top product PCNA Primary Antibody
  • Application Notes
    This affinity purified antibody has been tested for use in ELISA and western blot. Specific conditions for reactivity should be optimized by the end user. Expect a band approximately 29-36 kDa in size corresponding to PCNA protein by western blotting in the appropriate cell lysate or extract.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1.69 mg/mL
    Buffer
    0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
  • Target
    PCNA (Proliferating Cell Nuclear Antigen (PCNA))
    Alternative Name
    PCNA (PCNA Products)
    Background
    The proliferating cell nuclear antigen (PCNA) is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the processibility of DNA polymerase during elongation of the leading strand.  PCNA is expressed in the nucleus of all proliferating cells and is pivotal for DNA synthesis and cell cycle progression. In response to DNA damage, PCNA is mono-ubiquitinated and is involved in mismatch-provoked excision.  PCNA is a useful marker for DNA synthesis and is highly conserved among most species.
    Synonyms: PCNA, proliferating cell nuclear antigen, cyclin
    Gene ID
    5111, 33239451
    UniProt
    P12004
    Pathways
    Telomere Maintenance, DNA Damage Repair, Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA, Autophagy
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