SLIT3 antibody (AA 1164-1177)

Catalog No. ABIN129655

Product Details anti-SLIT3 Antibody

Target: SLIT3 (Slit Homolog 3 (SLIT3))

Binding Specificity: AA 1164-1177

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SLIT3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Cross-Reactivity: Rat (Rattus), Dog (Canine), Sheep (Ovine), Mouse (Murine)

Immunogen: This affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding aa 1164-1177 of Human SLIT-3 protein.

Isotype: IgG

Application Details

Application Notes: This affinity purified antibody has been tested for use in ELISA and by western blot.  Specific conditions for reactivity should be optimized by the end user. Expect a band at ~ 168 kDa corresponding to full length protein as well as multiple bands corresponding to isoforms of SLIT-3 by western blotting in the appropriate cell lysate or extract.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Target Details for SLIT3

Target: SLIT3 (Slit Homolog 3 (SLIT3))

Alternative Name: SLIT-3 (SLIT3 Products)

Synonyms: MGC146100 antibody, zgc:111911 antibody, MEGF5 antibody, SLIL2 antibody, SLIT1 antibody, Slit-3 antibody, slit2 antibody, Slil2 antibody, Slit1 antibody, Megf5 antibody, slit guidance ligand 3 antibody, slit homolog 3 (Drosophila) antibody, Slit3 antibody, slit3 antibody, SLIT3 antibody, LOC100125612 antibody, Slit3 antibody

Background: SLIT-3 (also known as multiple epidermal growth factor-like domain 5 and Slit homolog 3 protein) is a Slit protein.  The 'slit' gene has been shown to play a critical role in central nervous system midline formation. In addition to SLIT3 there are two additional human 'slit' homologs, which are termed SLIT1 and SLIT2.  Each SLIT gene encodes a putative secreted protein, which contains conserved protein-protein interaction domains including leucine-rich repeats and epidermal growth factor-like motifs, similar to those of the Drosophila protein.  SLIT proteins may also participate in the formation and maintenance of the nervous and endocrine systems by protein-protein interactions.  Slit-3 is a secreted protein predominantly expressed in thyroid.  Multiple isoforms have been reported for this product.
Synonyms: FLJ10764 antibody, KIAA0814 antibody, MEGF 5 antibody, MEGF5 antibody, Multiple epidermal growth factor-like domains 5 antibody, SLIL 2 antibody

Gene ID: 6586, 11321571

UniProt: O75094

Pathways: Regulation of Cell Size