DLL1 antibody (AA 155-173)

Catalog No. ABIN129638

Product Details anti-DLL1 Antibody

Target: DLL1 (delta-Like 1 (DLL1))

Binding Specificity: AA 155-173

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DLL1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Cross-Reactivity: Rat (Rattus), Human, Chicken

Characteristics: Concentration Definition: by UV absorbance at 280 nm

Immunogen: This affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to amino acids 155-173 of Mouse DELTA-1. DELTA-1 is a mouse homolog of the Notch Delta ligand and is a member of the delta/serrate/jagged family. It plays a role in mediating cell fate decisions during hematopoiesis. It may play a role in cell-to-cell communication. Swiss Prot accession Q61483. Expected to cross-react with rat, human and chicken.

Isotype: IgG

Application Details

Application Notes: Anti-DELTA-1 Antibody has been tested for use in ELISA against the immunizing peptide.  It is expected that anti-Delta-1 antibody will be reactive in western blot assays Reactivity in other immunoassays is unknown.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

References for anti-DLL1 antibody (ABIN129638)

Meliou, Kerezoudis, Tosios, Kiaris: "Notch 1 Receptor, Delta 1 Ligand and HES 1 Transcription Factor are Expressed in the Lining Epithelium of Periapical Cysts (Preliminary Study)." in: The open dentistry journal, Vol. 4, pp. 153-8, (2011) (PubMed).

Zhang, Zeng, Zhang, Jiao, Li, Jing, Ouyang, Yuan, Chai, Che, Zhang, Yang: "Suppressor of cytokine signaling 3 promotes bone marrow cells to differentiate into CD8+ T lymphocytes in lung tissue via up-regulating Notch1 expression." in: Cancer research, Vol. 69, Issue 4, pp. 1578-86, (2009) (PubMed).

Target Details for DLL1

Target: DLL1 (delta-Like 1 (DLL1))

Alternative Name: DELTA-1 (DLL1 Products)

Synonyms: X-delta-1 antibody, XDelta1 antibody, Xdelta-1 antibody, delta antibody, delta-1 antibody, delta1 antibody, x-delta antibody, DELTA1 antibody, DL1 antibody, Delta antibody, DLK antibody, DLK-1 antibody, Delta1 antibody, FA1 antibody, PREF1 antibody, Pref-1 antibody, ZOG antibody, pG2 antibody, DLL1 antibody, AW742678 antibody, DlkI antibody, Ly107 antibody, Peg9 antibody, SCP1 antibody, pref-1 antibody, delta-like 1 antibody, delta like canonical Notch ligand 1 antibody, delta like non-canonical Notch ligand 1 antibody, delta-like 1 L homeolog antibody, delta-like 1 (Drosophila) antibody, delta-like 1 homolog (Drosophila) antibody, dll1 antibody, DLL1 antibody, DLK1 antibody, Dll1 antibody, dll1.L antibody, Dlk1 antibody

Background: Delta-like protein 1 is a protein that in humans is encoded by the DLL1 gene. The Notch signaling pathway has pleiotropic functions during mammalian embryogenesis. It is required for the patterning and differentiation of the presomitic and somitic paraxial mesoderm and of the neural tube. DLL1 is a human homolog of the Notch Delta ligand and is a member of the delta/serrate/jagged family. It plays a role in mediating cell fate decisions during hematopoiesis, and has been shown to have a role in cell-to-cell communication. Anti-Delta-like protein 1 antibody would be sutiable for researchers in Cell Biology and Signal Transduction.
Synonyms: Delta-like protein 1 antibody, Drosophila Delta homolog 1 antibody

Gene ID: 13388

UniProt: Q61483

Pathways: Notch Signaling, Stem Cell Maintenance