DIA2 antibody (AA 1085-1101)
DIA2
Reactivity: Human
ELISA, WB
Host: Rabbit
Polyclonal
unconjugated
1 image
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- Target See all DIA2 products
- DIA2 (DIA-2 (DIA2))
- Binding Specificity
- AA 1085-1101
- Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This DIA2 antibody is un-conjugated
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Application
- ELISA, Western Blotting (WB)
- Characteristics
- Concentration Definition: by UV absorbance at 280 nm
- Immunogen
- This affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding aa 1085-1101 of Human DIA-2.
- Isotype
- IgG
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- Application Notes
- This affinity purified antibody has been tested for use in ELISA and by western blot. Specific conditions for reactivity should be optimized by the end user. Expect a band approximately 125 kDa in size corresponding to DIA-2 by western blotting in the appropriate cell lysate or extract. Alternate splice variants have been described for this protein. This antibody will only react with DIA-156 (isoform 1 of DIA-2).
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1.4 mg/mL
- Buffer
- 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
- Preservative
- Sodium azide
- Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
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- Target
- DIA2 (DIA-2 (DIA2))
- Alternative Name
- DIA-2 (DIA2 Products)
- Synonyms
- AN antibody, AUNA1 antibody, DIA2 antibody, DRF3 antibody, NSDAN antibody, diap3 antibody, mDia2 antibody, diaphanous related formin 3 antibody, DIAPH3 antibody
- Background
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DIA-2 (also called DIA drome, Dia2, DIAPH2, Diaphanous 2, Diaphanous related formin 2, Diaphorase 2, DRF2, POF and POF2) may play a role in the development and normal function of the ovaries. Mutations of this gene have been linked to premature ovarian failure. Alternative splicing results in two protein isoforms. Furthermore, each splice variant undergoes additional splicing in the 3' UTR. Overall 4 splice variants have been described. DIA-2 is expressed in testis, ovary, small intestine, prostate, lung, liver, kidney and leukocytes and can be found from E16 in ovary and testis and during P6-P16 during differentiation of ovarian follicles. Isoform 1 is referred to as DIA-156, whereas isoform 2 is called DIA-12C.
Synonyms: DIA-2, DIA drome, Dia2, DIAPH2, Diaphanous 2, Diaphanous related formin 2, Diaphorase 2, DRF2, POF and POF2 - Gene ID
- 1730, 5803003
- UniProt
- O60879
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