ATAD5 antibody (AA 63-76)

Catalog No. ABIN129617

Product Details anti-ATAD5 Antibody

Target: ATAD5 (ATPase Family, AAA Domain Containing 5 (ATAD5))

Binding Specificity: AA 63-76

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ATAD5 antibody is un-conjugated

Application: ELISA, Western Blotting (WB)

Characteristics: Concentration Definition: by UV absorbance at 280 nm

Immunogen: This affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to amino acids 63-76 of Human Elg 1.

Isotype: IgG

Application Details

Application Notes: This affinity purified antibody has been tested for use in ELISA and western blot.  Specific conditions for reactivity should be optimized by the end user. Expect a band approximately 120 kDa in size corresponding to Elg1 by western blotting in the appropriate cell lysate or extract.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.50 mg/mL

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Target Details for ATAD5

Target: ATAD5 (ATPase Family, AAA Domain Containing 5 (ATAD5))

Alternative Name: ELG-1 (ATAD5 Products)

Synonyms: C17orf41 antibody, ELG1 antibody, FRAG1 antibody, C130052G03Rik antibody, Gm17 antibody, RGD1561464 antibody, ATAD5 antibody, Si:ch211-11k18.10 protein-like antibody, atad5 antibody, cb14 antibody, im:7138471 antibody, sb:cb14 antibody, si:ch211-11k18.10 antibody, wu:fi03a11 antibody, dkeyp-97g3.4 antibody, fb23b03 antibody, wu:fb23b03 antibody, zgc:66453 antibody, ATPase family, AAA domain containing 5 antibody, ATPase family, AAA domain containing 5a antibody, ATPase family, AAA domain containing 5b antibody, ATAD5 antibody, Atad5 antibody, atad5a antibody, atad5b antibody

Background: ELG1 (also known as ATP(GTP)-binding protein or Chromosome fragility associated gene 1) is involved in a novel RFC complex that is probably involved in DNA damage and repair by ensuring replication fidelity. This antibody detects a band at about 120kDa in Hela, A431, Jurkat and HEK193 cells. This corresponds to the band size seen in Kanellis P et al. It remains unclear why the band size detected is much less than the 207kDa predicted in the protein sequence corresponding to CACC44537.2 (Q96QE3), but as our results correspond to those seen in Kanellis P et al. it is likely that the 120 kDa target is ELG1.
Synonyms: ATP(GTP)-binding protein, Chromosome fragility associated gene

Gene ID: 79915, 21615526

UniProt: Q96QE3