FANCF antibody (Internal Region)

Catalog No. ABIN129610

Supplier Product No.: 600-401-674

Product Details anti-FANCF Antibody

Target: FANCF (Fanconi Anemia, Complementation Group F (FANCF))

Binding Specificity: Internal Region

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FANCF antibody is un-conjugated

Application: ELISA, Western Blotting (WB)

Supplier Product No.: 600-401-674

Supplier: Rockland

Purpose: FANCF Antibody

Cross-Reactivity (Details): This affinity purified antibody is directed against human FANCF protein.

Characteristics: Synonyms: rabbit anti-FANCF antibody, FANC-F, FAC-F, FACF antibody, FAF antibody, Fanconi anemia complementation group F antibody, Fanconi anemia group F protein antibody, MGC126856 antibody, Protein FACF

Purification: The product was affinity purified from monospecific antiserum by immunoaffinity chromatography.

Sterility: Sterile filtered

Immunogen:

Immunogen: This affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to an internal amino acid sequence of human FANCF.

Immunogen Type: Conjugated Peptide

Isotype: IgG

Application Details

Application Notes:

Application Note: This affinity purified antibody has been tested for use in ELISA and by western blot.  Specific conditions for reactivity should be optimized by the end user. Expect a band approximately 42 kDa in size corresponding to FANCF by western blotting in the appropriate human tissue.

Western Blot Dilution: 1:1000

ELISA Dilution: User Optimized

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer:

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Stabilizer: None

Preservative: 0.01 % (w/v) Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

Expiry Date: 12 months

Target Details for FANCF

Target: FANCF (Fanconi Anemia, Complementation Group F (FANCF))

Alternative Name: FANCF (FANCF Products)

Background: Background: FANCF (also called Protein FACF or Fanconi Anemia Group F protein) is involved in DNA repair, perhaps specifically with post-replication repair or a cell cycle checkpoint function.  FANCF has also been implicated in interstrand DNA cross-link repair and in the maintenance of normal chromosome stability.  FANCF belongs to the multi-subunit Fanconi Anemia (FA) complex composed of FANCA, FANCB, FANCC, FANCE, FANCF, FANCG, FANCL/PHF9 and FANCM.  The complex is not found in FA patients. FANCF is found within the nucleus.  Defects in FANCF include Fanconi Anemia - Complementation Group F and Fanconi Anemia - Complementation Group A. Anti-FANCF antibody is useful for researchers interested in Ubiquitin, DNA repair, BRCA1, and Cell cycle checkpoint research.

Gene ID: 2188, 23821547

UniProt: Q9NPI8

Pathways: DNA Damage Repair