FANCC antibody (AA 96-112)

Catalog No. ABIN129608

Product Details anti-FANCC Antibody

Target: FANCC (Fanconi Anemia, Complementation Group C (FANCC))

Binding Specificity: AA 96-112

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FANCC antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Cross-Reactivity: Chimpanzee

Characteristics: Concentration Definition: by UV absorbance at 280 nm

Immunogen: This affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to amino acids 96-112 of Human FANCC.

Isotype: IgG

Application Details

Application Notes: This affinity purified antibody has been tested for use in ELISA and by western blot.  Specific conditions for reactivity should be optimized by the end user. Expect a band approximately 63 kDa in size corresponding to FANCC by western blotting in the appropriate human tissue.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.45 mg/mL

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Target Details for FANCC

Target: FANCC (Fanconi Anemia, Complementation Group C (FANCC))

Alternative Name: FANCC (FANCC Products)

Synonyms: zgc:154105 antibody, FANCC antibody, fa3 antibody, fac antibody, facc antibody, FA3 antibody, FAC antibody, FACC antibody, BB116513 antibody, Facc antibody, Fanconi anemia complementation group C antibody, Fanconi anemia, complementation group C antibody, Fanconi anemia complementation group C L homeolog antibody, FANCC antibody, fancc antibody, fancc.L antibody, Fancc antibody

Background: FANCC (also called Protein FACC or Fanconi Anemia Group C protein) is involved in DNA repair, perhaps specifically with post-replication repair or a cell cycle checkpoint function.  FANCC may also be implicated in interstrand DNA cross-link repair and in the maintenance of normal chromosome stability.  FANCC belongs to the multi-subunit Fanconi Anemia (FA) complex composed of FANCA, FANCB, FANCC, FANCE, FANCF, FANCG, FANCL/PHF9 and FANCM.  FANCC is mainly found within the nucleus although some protein is localized in the cytoplasm.  This protein is ubiquitously expressed.  Defects in FANCC are a cause of Fanconi anemia (FA). FA is a genetically heterogeneous, autosomal recessive disorder characterized by progressive pancytopaenia, a diverse assortment of congenital malformations, and
Synonyms: bA80I15.1 antibody, FA 3 antibody, FA3 antibody, FAC antibody, FACC antibody, Fanconi anemia complementation group C antibody

Gene ID: 2176, 56118236

UniProt: Q00597

Pathways: DNA Damage Repair