FANCG antibody (AA 1-12)

Catalog No. ABIN129607

Product Details anti-FANCG Antibody

Target: FANCG (Fanconi Anemia Complementation Group G (FANCG))

Binding Specificity: AA 1-12

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FANCG antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Cross-Reactivity: Chimpanzee

Characteristics: Concentration Definition: by UV absorbance at 280 nm

Immunogen: This affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to amino acids 1-12 of human FANCG protein.

Isotype: IgG

Application Details

Application Notes: This affinity purified antibody has been tested for use in ELISA, immunohistochemistry and by western blot.  Specific conditions for reactivity should be optimized by the end user. Expect a band approximately 69 kDa in size corresponding to FANCG by western blotting in the appropriate human tissue.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.93 mg/mL

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Target Details for FANCG

Target: FANCG (Fanconi Anemia Complementation Group G (FANCG))

Alternative Name: FANCG (FANCG Products)

Synonyms: xFANCG antibody, FAG antibody, XRCC9 antibody, AU041407 antibody, Xrcc9 antibody, Fanconi anemia complementation group G S homeolog antibody, Fanconi anemia complementation group G antibody, Fanconi anemia, complementation group G antibody, fancg.S antibody, FANCG antibody, Fancg antibody

Background: FANCG (also called Protein FACG or DNA-repair protein XRCC9) is involved in DNA repair, perhaps specifically with post-replication repair or a cell cycle checkpoint function. FANCG may also be implicated in interstrand DNA cross-link repair and in the maintenance of normal chromosome stability. This protein may also function as a tumor suppressor gene. FANCG belongs to the multi-subunit Fanconi Anemia (FA) complex composed of FANCA, FANCB, FANCC, FANCE, FANCF, FANCG, FANCL/PHF9 and FANCM. FANCG contains a 5-prime GC-rich untranslated region characteristic of housekeeping genes. The putative 622-amino acid protein has a leucine-zipper motif at its N-terminus. FANCG is mainly found within the nucleus although some protein is localized in the cytoplasm.  This protein is highly expressed in testis and thymus and is also found in lymphoblasts. Fanconi anemia is an
Synonyms: DNA repair protein XRCC9 antibody, DNA-repair protein XRCC9 antibody, FAG antibody, Fanconi anaemia complementation group G antibody, Protein FACG antibody

Gene ID: 2189, 4759336

UniProt: O15287

Pathways: DNA Damage Repair