HUS1B antibody (AA 104-117)

Catalog No. ABIN129605

Product Details anti-HUS1B Antibody

Target: HUS1B (HUS1 Checkpoint Homolog B (HUS1B))

Binding Specificity: AA 104-117

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HUS1B antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Cross-Reactivity: Mouse (Murine), Rat (Rattus)

Characteristics: Concentration Definition: by UV absorbance at 280 nm

Immunogen: This affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to amino acids 104-117 of human Hus1B protein.

Isotype: IgG

Application Details

Application Notes: This affinity-purified antibody has been tested for use in ELISA and western blot.  Specific conditions for reactivity should be optimized by the end user. Expect a band approximately 38 kDa in size corresponding to Hus1B protein by western blotting in the appropriate cell lysate or extract.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.75 mg/mL

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Target Details for HUS1B

Target: HUS1B (HUS1 Checkpoint Homolog B (HUS1B))

Alternative Name: Hus1B (HUS1B Products)

Synonyms: HUS1B antibody, RP11-532F6.1 antibody, HUS1 checkpoint clamp component B antibody, HUS1B antibody, Hus1b antibody

Background: The protein encoded by the Hus1B gene is most closely related to HUS1, a component of a cell cycle checkpoint protein complex involved in cell cycle arrest in response to DNA damage. This protein can interact with the checkpoint protein RAD1 but not with RAD9. Over expression of this protein has been shown to induce cell death, which suggests a related but distinct role of this protein, as compared to HUS1. Hus1B is expressed strongly in testis, less in spleen, thymus, prostate, colon and leukocytes.
Synonyms: Checkpoint protein HUS1B hHUS1B

Gene ID: 135458, 31077215

UniProt: Q8NHY5