DCLRE1C antibody (AA 482-495)
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- Target See all DCLRE1C Antibodies
- DCLRE1C (DNA Cross-Link Repair 1C (DCLRE1C))
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Binding Specificity
- AA 482-495
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Reactivity
- Human
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Host
- Goat
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Clonality
- Polyclonal
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Conjugate
- This DCLRE1C antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- Characteristics
- Concentration Definition: by UV absorbance at 280 nm
- Immunogen
- This affinity purified antibody was prepared from whole goat serum produced by repeated immunizations with a synthetic peptide corresponding aa 482-495 of Human ARTEMIS (DCLRE1C DNA cross-link repair 1C).
- Isotype
- IgG
- Top Product
- Discover our top product DCLRE1C Primary Antibody
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- Application Notes
- This affinity purified antibody has been tested for use in ELISA, immunohistochemistry and western blotting. Reactivity in other immunoassays is unknown. This antibody detects a band of approximately 90 kDa (predicted molecular weight: 78 kDa).
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1.2 mg/mL
- Buffer
- 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
- Preservative
- Sodium azide
- Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
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- Target
- DCLRE1C (DNA Cross-Link Repair 1C (DCLRE1C))
- Alternative Name
- Artemis (DCLRE1C Products)
- Synonyms
- artemis antibody, A-SCID antibody, DCLREC1C antibody, RS-SCID antibody, SCIDA antibody, SNM1C antibody, hSNM1C antibody, Snm1l antibody, nuclease antibody, 9930121L06Rik antibody, AI661365 antibody, Art antibody, DNA cross-link repair 1C antibody, DCLRE1C antibody, Dclre1c antibody
- Background
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Artemis has a role in T and B lymphocyte immunodeficiency and in predisposition to lymphoma through the NHEJ pathway of DNA repair. DNA-PKcs regulates Artemis by both phosphorylation and complex formation to permit enzymatic activities that are critical for the hairpin-opening step of V(D)J recombination and for the 5' and 3' overhang processing in non-homologous DNA end joining.
Synonyms: A SCID antibody, A SCID protein antibody, Artemis protein antibody, ASCID antibody, DCLRE1C antibody, DCLRE1C DNA cross link repair 1C antibody, DCLRE1C protein antibody - Gene ID
- 64421, 76496495
- UniProt
- Q96SD1
- Pathways
- DNA Damage Repair
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