RAD23A antibody (AA 122-135)

Catalog No. ABIN129556

Product Details anti-RAD23A Antibody

Target: RAD23A (RAD23 Homolog A (RAD23A))

Binding Specificity: AA 122-135

Reactivity: Human

Host: Goat

Clonality: Polyclonal

Conjugate: This RAD23A antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Characteristics: Concentration Definition: by UV absorbance at 280 nm

Immunogen: This affinity purified antibody was prepared from whole goat serum produced by repeated immunizations with a synthetic peptide corresponding aa 122-135 of human HR23A protein.

Isotype: IgG

Application Details

Application Notes: This affinity purified antibody has been tested for use in ELISA and by western blot.  Specific conditions for reactivity should be optimized by the end user. Expect a band approximately 60 kDa in size corresponding to HR23A by western blotting in the appropriate cell lysate or extract.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.2 mg/mL

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

References for anti-RAD23A antibody (ABIN129556)

Zhu, Wani, Arab, El-Mahdy, Ray, Wani: "Chromatin restoration following nucleotide excision repair involves the incorporation of ubiquitinated H2A at damaged genomic sites." in: DNA repair, Vol. 8, Issue 2, pp. 262-73, (2009) (PubMed).

Target Details for RAD23A

Target: RAD23A (RAD23 Homolog A (RAD23A))

Alternative Name: HR23A (RAD23A Products)

Synonyms: rad23a antibody, wu:fe11h06 antibody, zgc:92001 antibody, RAD23A antibody, HHR23A antibody, HR23A antibody, 2310040P19Rik antibody, AL024030 antibody, mHR23A antibody, RAD23 homolog A, nucleotide excision repair protein a antibody, RAD23 homolog A, nucleotide excision repair protein antibody, rad23aa antibody, RAD23A antibody, Rad23a antibody

Background: HR23A (also known as UV excision repair protein RAD23 homolog A) is one of two human homologs of Saccharomyces cerevisiae Rad23 (hHR23A and hHR23B), a protein involved in nucleotide excision repair (NER). This protein was shown to interact with, and elevate the nucleotide excision activity of 3-methyladenine-DNA glycosylase (MPG), which suggested a role in DNA damage recognition in base excision repair. This protein contains an N-terminal ubiquitin-like domain, which was reported to interact with 26S proteasome, as well as with ubiquitin protein ligase E6AP, and thus suggests that this protein may be involved in the ubiquitin mediated proteolytic pathway in cells.
Synonyms: hHR 23A antibody, MGC111083 antibody, RAD23 homolog A antibody, RAD23 yeast homolog A antibody, RAD23a antibody

Gene ID: 5886, 4826964

UniProt: P54725

Pathways: DNA Damage Repair