Anti-RREB1 antibody was prepared from whole rabbit serum produced by repeated immunizations with a recombinant protein corresponding to mouse RREB1 protein. Immunogentype:Recombinant
RREB1
Reactivity: Human
WB, ELISA
Host: Rabbit
Polyclonal
Biotin
Application Notes
This Protein A purified antibody has been tested for use in ELISA and by western blot. Specific conditions for reactivity should be optimized by the end user. Expect a predominant band approximately 90-180 kDa in size corresponding to RREB1 by western blotting in the appropriate cell lysate or extract. Multiple bands seen in the above western blot may indicate cross-reactive isoforms or truncated protein products.
Restrictions
For Research Use only
Format
Liquid
Buffer
0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Flajollet, Poras, Carosella, Moreau: "RREB-1 is a transcriptional repressor of HLA-G." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 183, Issue 11, pp. 6948-59, (2009) (PubMed).
Kuppuswamy, Vijayalingam, Zhao, Zhou, Subramanian, Ryerse, Chinnadurai: "Role of the PLDLS-binding cleft region of CtBP1 in recruitment of core and auxiliary components of the corepressor complex." in: Molecular and cellular biology, Vol. 28, Issue 1, pp. 269-81, (2008) (PubMed).
Target
RREB1
(Ras Responsive Element Binding Protein 1 (RREB1))
This antibody is designed, produced, and is suitable for Cancer, Neuroscience, and Signal Transduction research. RREB1 (also known as RAS-responsive element binding protein 1 and Raf responsive zinc finger protein) is a transcription factor that binds specifically to the distal RAS-responsive element (RRE) of gene promoters. May be involved in Ras/Raf-mediated cell differentiation by enhancing calcitonin expression. Synonyms: FINB antibody, Finger protein in nuclear bodies antibody, LZ321 antibody, Raf responsive zinc finger protein LZ321 antibody, RAS responsive element binding protein 1 antibody