Thyroglobulin antibody

Catalog No. ABIN129506

Product Details anti-Thyroglobulin Antibody

Target: Thyroglobulin (TG)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Thyroglobulin antibody is un-conjugated

Application: Immunohistochemistry (IHC), ELISA, Western Blotting (WB), Immunoprecipitation (IP)

Cross-Reactivity: Mouse (Murine), Rat (Rattus), Dog (Canine)

Characteristics: Concentration Definition: by UV absorbance at 280 nm

Immunogen: This protein A purified monoclonal antibody was produced by repeated immunizations with human thyroglobulin protein.
Immunogentype:Native

Clone: 2H11

Isotype: IgG

Application Details

Application Notes: This antibody is suitable for the detection of thyroglobulin in ELISA, immunohistochemistry, immunoblotting and immunoprecipitation. For immunohistochemistry, both frozen sections and formalin fixed, paraffin-embedded tissue sections can be used without epitope retrieval or enzyme digestion.  This antibody is specific for the 330 kDa thyroglobulin protein.  Thyroglobulin shows a cytoplasmic localization.  Thyroid tissue can be used as a positive control.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.6 mg/mL

Buffer: 0.02 M Potassium Phosphate, 0.5 M Sodium Chloride, pH 7.2

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Target Details for Thyroglobulin

Target: Thyroglobulin (TG)

Alternative Name: Thyroglobulin (TG Products)

Background: Thyroglobulin (Tg) is synthesized by the follicular epithelial cells of the thyroid and secreted from the thyroid gland with the stimulation of TSH and/or thyroid stimulating immunoglobulins.  Thyroglobulin is a prognostic marker for Graves` disease. Thyroglobulin antibody has been useful in the positive identification of thyroid carcinomas of the papillary and follicular types.
Synonyms: AITD 3 antibody, AITD3 antibody, hTG antibody, TDH3 antibody, Tg antibody, TGN antibody

Gene ID: 7038

UniProt: P01266

Pathways: Thyroid Hormone Synthesis