GPR137B antibody (C-Term)

Catalog No. ABIN122456

Product Details anti-GPR137B Antibody

Target: GPR137B (G Protein-Coupled Receptor 137B (GPR137B))

Binding Specificity: C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GPR137B antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Specificity: Reacts with G Protein-Coupled Receptor TM7SF1 (Family: GPCR, Subfamily: Orphan-U)

Cross-Reactivity (Details): Species reactivity (tested):Human.

Purification: Immunoaffinity Chromatography

Immunogen: Synthetic peptide - KLH conjugated

Application Details

Application Notes: Immunocytochemistry. Immunohistochemistry on formalin-fixed paraffin embedded tissues: 5-12 μg/mL Antigen retrieval: Steam slides in 0.01 M sodium citrate buffer, pH 6.0, at 99-100 °C for 20 min. Remove from heat and let stand at room temperature in buffer for 20 min. Rinse in 1x TBS with Tween (TBST) for 1 min. at room temperature.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. Further Comments: This product was originally produced by MBL International.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: PBS, pH 7.7, containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-80 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -70 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Expiry Date: 12 months

Target Details for GPR137B

Target: GPR137B (G Protein-Coupled Receptor 137B (GPR137B))

Alternative Name: GPR137B / TM7SF1 (GPR137B Products)

Background: TM7SF1 is an Orphan-U GPCR with an unknown ligand. This receptor has been shown to be upregulated during kidney development. TM7SF1 has been reported to be expressed in adult kidney and heart, but not in fetal kidney. ESTs have been isolated from a wide variety of tissues, including B-cell/lung/testis, brain, connective tissue, ear, embryo, eye, gall bladder, kidney, liver/spleen, lung, melanocyte/uterus/fetal heart, nerve, pineal, placenta, skin, spleen, testis, tonsil, and vessel libraries.Synonyms: Integral membrane protein GPR137B, Transmembrane 7 superfamily member 1 protein

Gene ID: 7107

UniProt: O60478