LPHN3 antibody (Cytoplasmic Domain)

Catalog No. ABIN122280

Product Details anti-LPHN3 Antibody

Target: LPHN3 (Latrophilin 3 (LPHN3))

Binding Specificity: Cytoplasmic Domain

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LPHN3 antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificity: Reacts with Latrophilin-3 (family: GPCR, subfamily: Orphan-B)

Purification: Peptide immunogen affinity column

Immunogen: Synthetic peptide - KLH conjugated

Application Details

Application Notes: Immunohistochemistry with formalin fixed paraffin embedded tissues: 2 μg/mL Antigen retrieval: Steam slides in 0.01 M sodium citrate buffer, pH 6.0, at 99-100 °C for 20 min. Remove from heat and let stand at room temperature in buffer for 20 min. Rinse in 1x TBS with Tween (TBST) for 1 min. at room temperature.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. Further Comments: This product was originally produced by MBL International.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: PBS, pH 7.7, containing 0.01 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-80 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -70 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Expiry Date: 12 months

Target Details for LPHN3

Target: LPHN3 (Latrophilin 3 (LPHN3))

Alternative Name: Latrophilin-3 (LPHN3 Products)

Synonyms: LPHN3 antibody, CIRL3 antibody, LEC3 antibody, 5430402I23Rik antibody, CIRL-3 antibody, D130075K09Rik antibody, Gm1379 antibody, mKIAA0768 antibody, Cirl3 antibody, Lec3 antibody, LPHH3 antibody, adhesion G protein-coupled receptor L3 antibody, ADGRL3 antibody, LOC100554073 antibody, Adgrl3 antibody

Background: Latrophilin-3 is a brain-specific, Ca2+-independent Orphan-B Receptor with an unknown ligand. Unlike the other two latrophilins, Latrophilin-3 does not bind alpha-latrotoxin. Latrophilin-3, like its isoforms, shares homology with lectin, olfactomedin, and transmembrane domains, and possesses variable C-termini and various alternative-splicing sites. Latrophilin-3 has been reported in brain, heart, placenta, and lung. ESTs have been isolated from B-cell / lung / testis, brain, ear, eye, heart, heart / melanocyte / uterus, kidney, lung, nerve, placenta, and testis libraries.Synonyms: Calcium-independent alpha-latrotoxin receptor 3, KIAA0768, LEC3, LPHN3, Latrophilin-3, Lectomedin-3

Gene ID: 23284

UniProt: Q9HAR2