PPM1A antibody
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- Target See all PPM1A Antibodies
- PPM1A (Protein Phosphatase, Mg2+/Mn2+ Dependent, 1A (PPM1A))
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Reactivity
- Human, Mouse
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This PPM1A antibody is un-conjugated
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Application
- Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
- Specificity
- This antibody detects Protein Phosphatase 2C alpha (PP2C alpha).
- Purification
- Protein-G affinity chromatography
- Immunogen
- Recombinant human PP2C alpha protein
- Clone
- P6c7
- Isotype
- IgG2b
- Top Product
- Discover our top product PPM1A Primary Antibody
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- Application Notes
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ELISA. Western blot: Recommended dilution range: 1:250 approx. 1:1000. Recommended starting dilution: 1:250. Immunoprecipitation.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1.0 mg/mL
- Buffer
- PBS, pH 7.4, containing 0.09 % Sodium Azide as preservative.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C/-20 °C
- Storage Comment
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Store the antibody at 2-8 °C for one month or at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf Life: one year from despatch. - Expiry Date
- 12 months
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- Target
- PPM1A (Protein Phosphatase, Mg2+/Mn2+ Dependent, 1A (PPM1A))
- Alternative Name
- Protein Phosphatase 1A / PPM1A (PPM1A Products)
- Background
- Protein phosphatase 2C(PP2Cα) is a Mn2+- or Mg2+-dependent protein serine/threonine phosphatase that inhibits the human stress-responsive p38 and JNK MAPK pathways and regulates cellular stress response in eukaryotes. The PPM (metal-dependent protein phosphatase) family of Ser/Thr protein phosphatases have recently been shown to down-regulate the stress response pathways in eukaryotes. Within the stress pathway, key signaling kinases, which are activated by protein phosphorylation, have been proposed as the in vivo substrates of PP2C, the prototypical member of the PPM family.Synonyms: PP2C-alpha, PPPM1A, Protein phosphatase 2C isoform alpha, Protein phosphatase IA
- UniProt
- P35813
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