MHC Class I RT1.Aa alpha-Chain (RT1.AA) antibody
-
- Target See all MHC Class I RT1.Aa alpha-Chain (RT1.AA) Antibodies
- MHC Class I RT1.Aa alpha-Chain (RT1.AA)
- Reactivity
- Rat
-
Host
- Mouse
-
Clonality
- Monoclonal
-
Conjugate
- Un-conjugated
- Application
- Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunoprecipitation (IP)
- Purification
- Protein G Chromotraphy
- Immunogen
- Rat spleen membrane glycoproteins depleted of Ia-A antigens. Donor: BALB/c spleen. Fusion Partner: X63 Ag8.653
- Clone
- OX-18
- Isotype
- IgG1
- Top Product
- Discover our top product RT1.AA Primary Antibody
-
-
- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
-
- Concentration
- 1.0 mg/mL
- Buffer
- PBS
- Preservative
- Azide free
- Storage
- 4 °C/-20 °C
- Storage Comment
-
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing. Handle under aseptic conditions.
Shelf Life: one year from despatch. - Expiry Date
- 12 months
-
- Target
- MHC Class I RT1.Aa alpha-Chain (RT1.AA)
- Alternative Name
- MHC Class I (RT1Aa) (RT1.AA Products)
- Synonyms
- RTA antibody, Rt1.aa antibody, RT1 class I, locus A antibody, RT1-A antibody
- Background
- MHC Class I molecules play a central role in the immune system by presenting peptides derived from the endoplasmic reticulum lumen. MHC class I antigens are heterodimers consisting of one alpha chain (44 kDa) with beta 2 microglobulin (11.5 kDa). The antigen is expressed by all somatic cells at varying levels. MHC Class I molecules are expressed on most nucleated cells where they present endogenously synthesized antigenic peptides to CD8+ T lymphocytes, which are usually cytotoxic T cells. Fibroblasts or neurons however only show a low level of antigen.Synonyms: RT1 class I histocompatibility antigen AA alpha chain
-