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MHC Class I RT1.Aa alpha-Chain (RT1.AA) antibody

RT1.AA Reactivity: Rat FACS, IHC (fro), IP Host: Mouse Monoclonal OX-18 unconjugated
Catalog No. ABIN120718
  • Target See all MHC Class I RT1.Aa alpha-Chain (RT1.AA) Antibodies
    MHC Class I RT1.Aa alpha-Chain (RT1.AA)
    Reactivity
    Rat
    Host
    • 1
    Mouse
    Clonality
    • 1
    Monoclonal
    Conjugate
    • 1
    Un-conjugated
    Application
    Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunoprecipitation (IP)
    Purification
    Protein G Chromotraphy
    Immunogen
    Rat spleen membrane glycoproteins depleted of Ia-A antigens. Donor: BALB/c spleen. Fusion Partner: X63 Ag8.653
    Clone
    OX-18
    Isotype
    IgG1
    Top Product
    Discover our top product RT1.AA Primary Antibody
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Concentration
    1.0 mg/mL
    Buffer
    PBS
    Preservative
    Azide free
    Storage
    4 °C/-20 °C
    Storage Comment
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing. Handle under aseptic conditions.
    Shelf Life: one year from despatch.
    Expiry Date
    12 months
  • Target
    MHC Class I RT1.Aa alpha-Chain (RT1.AA)
    Alternative Name
    MHC Class I (RT1Aa) (RT1.AA Products)
    Synonyms
    RTA antibody, Rt1.aa antibody, RT1 class I, locus A antibody, RT1-A antibody
    Background
    MHC Class I molecules play a central role in the immune system by presenting peptides derived from the endoplasmic reticulum lumen. MHC class I antigens are heterodimers consisting of one alpha chain (44 kDa) with beta 2 microglobulin (11.5 kDa). The antigen is expressed by all somatic cells at varying levels. MHC Class I molecules are expressed on most nucleated cells where they present endogenously synthesized antigenic peptides to CD8+ T lymphocytes, which are usually cytotoxic T cells. Fibroblasts or neurons however only show a low level of antigen.Synonyms: RT1 class I histocompatibility antigen AA alpha chain
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