C5AR1 antibody

Catalog No. ABIN120011

Product Details anti-C5AR1 Antibody

Target: C5AR1 (Complement Component 5a Receptor 1 (C5AR1))

Reactivity: Rat

Host: Mouse

Clonality: Monoclonal

Conjugate: This C5AR1 antibody is un-conjugated

Application: Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro))

Specificity: This antibody recognises the CD88 cell surface receptor, also known as C5aR, which functions as a receptor for the C5a fragment of the complement factor C5.

Purification: Affinity chromatography on Protein G

Immunogen: Transfectants expressing rat CD88. Spleen cells from immunised BALB/c mice were fused with cells of the mouse Ag8.653 myeloma cell line

Clone: R63

Isotype: IgG1

Application Details

Application Notes: Flow Cytometry: 1/10 - 1/50, Use 10 μL of the suggested working dilution to label 10^6 cells in 100 μL. Immunohistochemistry on frozen sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: PBS, pH 7.4 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: This product is photosensitive and should be protected from light

Storage: 4 °C

Storage Comment: Store the antibody undiluted at 2-8 °C. DO NOT FREEZE!

Target Details for C5AR1

Target: C5AR1 (Complement Component 5a Receptor 1 (C5AR1))

Alternative Name: CD88 / C5R1 (C5AR1 Products)

Background: CD88 is expressed by cells of the myeloid lineage such as monocytes and macrophages.Synonyms: C5AR1, C5a anaphylatoxin chemotactic receptor, C5a-R, C5aR, Complement Component 5a Receptor 1

Gene ID: 113959

NCBI Accession: NP_446071

UniProt: P97520

Pathways: Complement System