PLAP antibody

Catalog No. ABIN119921

Product Details anti-PLAP Antibody

Target: PLAP (ALPP) (Placental Alkaline Phosphatase (ALPP))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This PLAP antibody is un-conjugated

Application: Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro)), Enzyme Immunoassay (EIA)

Specificity: SM2070P recognises placental alkaline phosphate, a 67 kDa isoform expressed in trophoblast cells of normal human placenta, in seminomas and in ovarian carcinoma. The H17E2 antibody has been widely used in immunolocalisation studies of germ cell tumours and may also be used in ELISA based assays for the measurement of soluble PLAP.

Purification: Affinity chromatography on Protein G

Immunogen: Placental membrane

Clone: H17E2

Isotype: IgG1

Application Details

Application Notes: ELISA. Flow Cytometry. Immunohistochemistry on frozen sections. Recommended Positive Control: placenta, seminoma
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: PBS containing 0.09 % Sodium

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for PLAP

Target: PLAP (ALPP) (Placental Alkaline Phosphatase (ALPP))

Abstract: ALPP Products

Background: Alkaline phosphatases are phosphodiesterases. The placental-specific isozyme of Alkaline Phosphatase (PLAP) is found in trophoblast cells of normal human mature placenta, seminomas of testis and ovarian carcinomas. Detection of alkaline phosphatase in serum is a marker for ovarian and testicular cancer.Synonyms: Alkaline phosphatase, Alkaline phosphatase Regan isozyme, PLAP-1, placental type

Gene ID: 250

NCBI Accession: NP_001623

UniProt: P05187