CD79b antibody

Catalog No. ABIN119705

Product Details anti-CD79b Antibody

Target: CD79b (CD79B) (CD79b Molecule, Immunoglobulin-Associated beta (CD79B))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD79b antibody is un-conjugated

Application: Flow Cytometry (FACS), Western Blotting (WB), Immunoprecipitation (IP)

Specificity: This antibody recognises an extracellular region of CD79b.

Purification: Affinity Chromatography on Protein A.

Immunogen: IgM complex isolated from Jo72-1 cells which have been transfected with human m, CD79a and CD79beta. Spleen cells from immunised mouse were fused with cells of the mouse NS-1 myeloma cell line.

Clone: AT105-1

Isotype: IgG1

Application Details

Application Notes: Flow Cytometry: 1/20, use 10 μL of the suggested working dilution to label 10^6 cells in 100 μL. Immunoprecipitation. ELISA.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: TRIS buffered saline pH 8.0 containing 0.09 % Sodium Azide as preservative.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for CD79b

Target: CD79b (CD79B) (CD79b Molecule, Immunoglobulin-Associated beta (CD79B))

Alternative Name: CD79b (CD79B Products)

Synonyms: B29 antibody, Ig-beta antibody, Igb antibody, Igbeta antibody, AGM6 antibody, IGB antibody, CD79B antigen antibody, CD79b molecule antibody, Cd79b antibody, CD79B antibody

Background: CD79b is a cell surface antigen expressed by B lymphocytes. The CD79b molecule (also known as Ig beta and B29) associates with CD79a to form a heterodimer that is non-covalently linked to surface immunoglobulin, forming the B-cell receptor (BCR) complex.Synonyms: B-Cell marker, B-cell antigen receptor complex-associated protein beta-chain, B-cell-specific glycoprotein B29, B29, IGB, Immunoglobulin-associated B29 protein

Gene ID: 974

NCBI Accession: NP_000617

UniProt: P40259

Pathways: BCR Signaling