Follicular Dendritic Cells antibody

Catalog No. ABIN119460

Product Details anti-Follicular Dendritic Cells Antibody

Target: Follicular Dendritic Cells

Reactivity: Rat

Host: Mouse

Clonality: Monoclonal

Conjugate: This Follicular Dendritic Cells antibody is un-conjugated

Application: Immunohistochemistry (Frozen Sections) (IHC (fro))

No Cross-Reactivity: Mouse (Murine)

Cross-Reactivity (Details): Species reactivity (tested):Rat.

Purification: Purified

Immunogen: Rat spleen cells. Spleen cells from immunised BALB/c mice were fused with cells of the Sp2/0-Ag14 mouse myeloma cell line.

Clone: ED5

Isotype: IgG1

Application Details

Application Notes: Immunohistochemistry on frozen sections: 1/260.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: PBS containing 0.09 % Sodium Azide as preservative.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for Follicular Dendritic Cells

Target: Follicular Dendritic Cells

Background: Follicular dendritic cells are cells that facilitate antigen recognition by B cells in follicles. This kind of dendritic cell is not bone marrow derived and is not a kind of blood cell. It is purely a resident of the follicles of secondary lymphoid organs. B cells form germinal centers around follicular dendritic cells in lymphoid organs. Dendritic cells form from monocytes, white blood cells which circulate in the body and, depending on the right signal, can turn into dendritic cells or macrophages. The monocytes in turn are formed from stem cells in the bone marrow.