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CD40 Ligand antibody
CD40LG
Reactivity: Human
FACS, Func
Host: Mouse
Monoclonal
MK13A4
unconjugated
Product Details anti-CD40 Ligand Antibody
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Target
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CD40 Ligand (CD40LG)
Reactivity
All reactivities for CD40 Ligand antibodies
Human
Host
All hosts for CD40 Ligand antibodies
Mouse
Clonality
All clonalities for CD40 Ligand antibodies
Monoclonal
Conjugate
All conjugates for CD40 Ligand antibodies
This CD40 Ligand antibody is un-conjugated
Application
All applications for CD40 Ligand antibodies
Flow Cytometry (FACS), Functional Studies (Func)
Specificity
This antibody recognises the CD154 cell surface antigen. Clone MK13A4 has been reported to block binding of CD40 ligand to its receptor CD40.
Clone
MK13A4
Isotype
IgG1
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Alternatives
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Application Details
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Application Notes
Flow Cytometry. Fuctional Assays. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions
For Research Use only
Handling
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Concentration
1.0 mg/mL
Buffer
PBS
Preservative
Azide free
Handling Advice
Avoid repeated freezing and thawing.
Storage
-20 °C
References for anti-CD40 Ligand antibody (ABIN119172)
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Bose, Dasgupta, Tarafder, Bandyopadhyay : "Microwave-processed nanocrystalline hydroxyapatite: simultaneous enhancement of mechanical and biological properties. " in: Acta biomaterialia , Vol. 6 , Issue 9 , pp. 3782-90 , (2010 ) (PubMed ).
Casati, Camisaschi, Novellino, Mazzocchi, Triebel, Rivoltini, Parmiani, Castelli : "Human lymphocyte activation gene-3 molecules expressed by activated T cells deliver costimulation signal for dendritic cell activation. " in: Journal of immunology (Baltimore, Md. : 1950) , Vol. 180 , Issue 6 , pp. 3782-8 , (2008 ) (PubMed ).
Target Details for CD40 Ligand
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Target
CD40 Ligand (CD40LG)
Alternative Name
CD154 / CD40L (CD40LG Products )
Synonyms
CD154 antibody, cd40l antibody, CD40L antibody, HIGM1 antibody, IGM antibody, IMD3 antibody, T-BAM antibody, TNFSF5 antibody, TRAP antibody, gp39 antibody, hCD40L antibody, CD40-L antibody, Cd40l antibody, Ly-62 antibody, Ly62 antibody, Tnfsf5 antibody, CD40 ligand antibody, TNF superfamily member 5 antibody, CD40LG antibody, cd40l antibody, Cd40lg antibody
Background
CD154 is a 32kD glycoprotein also known as CD40 ligand. CD154 is expressed on activated T lymphocytes, predominantly CD4+ve cells and also on some basophils and mast cells.Synonyms: CD40 ligand, CD40-L, CD40LG, GP39, T-cell antigen Gp39, TNF-related activation protein, TNFSF5, TRAP, Tumor necrosis factor ligand superfamily member 5
Gene ID
959
NCBI Accession
NP_000065
UniProt
P29965
Pathways
NF-kappaB Signaling , Production of Molecular Mediator of Immune Response , Cancer Immune Checkpoints
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