HLA-B27 antibody (FITC)

Catalog No. ABIN118936

Product Details anti-HLA-B27 Antibody (FITC)

Target: HLA-B27 (HLA Class I Histocompatibility Antigen, B-27 alpha Chain (HLA-B27))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This HLA-B27 antibody is conjugated to FITC

Application: Flow Cytometry (FACS)

Purification: Ion exchange chromatography

Immunogen: Immune complex precipitated from an HLA-B27 positive cell line (Bordin) by anti HLA antibody and staphylococcal protein A.

Clone: HLA-ABC-m3

Isotype: IgG2a

Application Details

Application Notes: Flow Cytometry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 50 µg/mL

Buffer: PBS, pH 7.4 containing 0.09 % Sodium Azide and 0.2 % Bovine Serum Albumin

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Dilute only prior to immediate use

Storage: 4 °C

Storage Comment: Store the antibody undiluted at 2-8 °C. DO NOT FREEZE! Freezing alkaline phosphatase conjugates will result in a substantial loss of enzymatic activity.

Target Details for HLA-B27

Target: HLA-B27 (HLA Class I Histocompatibility Antigen, B-27 alpha Chain (HLA-B27))

Alternative Name: HLA Class I B-27 alpha / HLA-B27 (HLA-B27 Products)

Synonyms: AS antibody, HLAB antibody, SPDA1 antibody, major histocompatibility complex, class I, B antibody, HLA-B antibody

Background: Involved in the presentation of foreign antigens to the immune system. HLA B belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta 2 microglobulin). The heavy chain is anchored in the membrane. Class I molecules play a central role in the immune system by presenting peptides derived from the endoplasmic reticulum lumen. They are expressed in nearly all cells.Synonyms: HLA-B, HLAB, MHC class I antigen B-27

Gene ID: 9606

UniProt: P03989

Pathways: Human Leukocyte Antigen (HLA) in Adaptive Immune Response