Caspase 1 p20 antibody (Biotin)
-
- Target See all Caspase 1 p20 products
- Caspase 1 p20
-
Reactivity
- Mouse
-
Host
- Mouse
-
Clonality
- Monoclonal
-
Conjugate
- This Caspase 1 p20 antibody is conjugated to Biotin
-
Application
- Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (IHC)
- Specificity
- Recognizes endogenous full-length and activated (p20 fragment) mouse caspase-1.
- Cross-Reactivity
- Mouse (Murine)
- Purification
- Purified from concentrated hybridoma tissue culture supernatant.
- Purity
- >95 % (SDS-PAGE)
- Immunogen
- Recombinant mouse caspase-1.
- Clone
- Casper-1
- Isotype
- IgG1
-
-
- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- In PBS containing 0.02 % sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
-
Short Term Storage: +4°C
Long Term Storage: -20°C
Stable for at least 1 year after receipt when stored at -20°C. - Expiry Date
- 12 months
-
-
The signaling adaptor BCAP inhibits NLRP3 and NLRC4 inflammasome activation in macrophages through interactions with Flightless-1." in: Science signaling, Vol. 12, Issue 581, (2020) (PubMed).
: "
-
The signaling adaptor BCAP inhibits NLRP3 and NLRC4 inflammasome activation in macrophages through interactions with Flightless-1." in: Science signaling, Vol. 12, Issue 581, (2020) (PubMed).
-
- Target
- Caspase 1 p20
- Alternative Name
- Caspase-1 p20 (Caspase 1 p20 Products)
- Background
- Caspase-1 is the best-described inflammatory caspase. It processes the cytokines interleukin-1beta (IL-1beta) and IL-18 and induces pyroptotic cell death. Caspase-1 is activated by multiprotein complexes called Inflammasomes in response to numerous stimuli that are detected through distinct inflammasomes. NLRC4 responds to cytosolic flagellin, murine NLRP1b responds to anthrax lethal toxin, AIM2 responds to cytosolic DNA and NLRP3 responds to a variety of agonists including crystals.
- UniProt
- P29452
-