Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@antibodies-online.com

Caspase 1 p20 antibody (Biotin)

Reactivity: Mouse WB, IP, IHC Host: Mouse Monoclonal Casper-1 Biotin
Catalog No. ABIN1169383
  • Target See all Caspase 1 p20 products
    Caspase 1 p20
    Reactivity
    • 51
    • 33
    • 32
    Mouse
    Host
    • 49
    • 3
    Mouse
    Clonality
    • 49
    • 3
    Monoclonal
    Conjugate
    • 6
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    This Caspase 1 p20 antibody is conjugated to Biotin
    Application
    • 42
    • 36
    • 26
    • 26
    • 10
    • 9
    • 6
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (IHC)
    Specificity
    Recognizes endogenous full-length and activated (p20 fragment) mouse caspase-1.
    Cross-Reactivity
    Mouse (Murine)
    Purification
    Purified from concentrated hybridoma tissue culture supernatant.
    Purity
    >95 % (SDS-PAGE)
    Immunogen
    Recombinant mouse caspase-1.
    Clone
    Casper-1
    Isotype
    IgG1
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    In PBS containing 0.02 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Short Term Storage: +4°C
    Long Term Storage: -20°C
    Stable for at least 1 year after receipt when stored at -20°C.
    Expiry Date
    12 months
  • Carpentier, Ni, Duggan, James, Cookson, Hamerman: "The signaling adaptor BCAP inhibits NLRP3 and NLRC4 inflammasome activation in macrophages through interactions with Flightless-1." in: Science signaling, Vol. 12, Issue 581, (2020) (PubMed).

  • Target
    Caspase 1 p20
    Alternative Name
    Caspase-1 p20 (Caspase 1 p20 Products)
    Background
    Caspase-1 is the best-described inflammatory caspase. It processes the cytokines interleukin-1beta (IL-1beta) and IL-18 and induces pyroptotic cell death. Caspase-1 is activated by multiprotein complexes called Inflammasomes in response to numerous stimuli that are detected through distinct inflammasomes. NLRC4 responds to cytosolic flagellin, murine NLRP1b responds to anthrax lethal toxin, AIM2 responds to cytosolic DNA and NLRP3 responds to a variety of agonists including crystals.
    UniProt
    P29452
You are here:
Support