CTRP5 antibody

Catalog No. ABIN1169281

Product Details anti-CTRP5 Antibody

Target: CTRP5 (C1QTNF5) (C1q and Tumor Necrosis Factor Related Protein 5 (C1QTNF5))

Reactivity: Human

Host: Guinea Pig

Clonality: Polyclonal

Conjugate: This CTRP5 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunoprecipitation (IP)

Specificity: Recognizes a N-terminal region of CTRP5 full-length protein. Detects bands of ~15 kDa and ~26 kDa by Western blot. This antibody is CTRP5-specific.

Cross-Reactivity: Human

Sterility: 0.2 μm filtered

Immunogen: Recombinant human CTRP5.

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: 0.2μm-filtered solution in PBS, pH 7.4. Contains no preservatives.

Preservative: Without preservative

Storage: 4 °C,-20 °C

Storage Comment: Short Term Storage: +4°C
Long Term Storage: -20°C
Stable for at least 6 months after receipt when stored at -20°C.

Expiry Date: 6 months

Target Details for CTRP5

Target: CTRP5 (C1QTNF5) (C1q and Tumor Necrosis Factor Related Protein 5 (C1QTNF5))

Alternative Name: CTRP5 (C1QTNF5 Products)

Background: CTRP5 (C1qTNF-related protein 5, C1QTNF5) belongs to a highly conserved family of adiponectin paralogs. CTRP5 mediates activation of AMP-activated protein kinase (AMPK) in muscle and liver cells, thereby regulating glucose and lipid metabolism. Serum levels of CTRP5 are significantly higher in obese/diabetic animal models compared to normal controls. Furthermore, CTRP5 may be a putative biomarker for mitochondrial dysfunction. Defects in C1QTNF5 are a cause of late-onset retinal degeneration (LORD).

UniProt: Q9BXJ0