TICAM2 antibody (AA 2-29)
(1 reference)-
- Target See all TICAM2 Antibodies
- TICAM2 (Toll-Like Receptor Adaptor Molecule 2 (TICAM2))
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Binding Specificity
- AA 2-29
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This TICAM2 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Specificity
- Recognizes human TRAM.
- Cross-Reactivity
- Human
- Immunogen
- Synthetic peptide corresponding to aa 2-29 (G2IGKSKINSCPLSLSWGKRHSVDTSPGY29) of human TRAM.
- Top Product
- Discover our top product TICAM2 Primary Antibody
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anti-Toll-Like Receptor Adaptor Molecule 2 (TICAM2) (C-Term) antibody
TICAM2 Reactivity: Human, Mouse, Rat WB, ICC, IHC (p), IHC (fro) Host: Rabbit Polyclonal unconjugated
anti-Toll-Like Receptor Adaptor Molecule 2 (TICAM2) (AA 1-235) antibodyTICAM2 Reactivity: Human ELISA, IHC Host: Rabbit Polyclonal unconjugated
anti-Toll-Like Receptor Adaptor Molecule 2 (TICAM2) (AA 150-200) antibodyTICAM2 Reactivity: Human, Mouse, Rat, Monkey, Cow, Opossum WB, IHC, IHC (p) Host: Rabbit Polyclonal unconjugated
anti-Toll-Like Receptor Adaptor Molecule 2 (TICAM2) (AA 1-235) antibodyTICAM2 Reactivity: Human WB, IP Host: Rabbit Polyclonal unconjugated
anti-Toll-Like Receptor Adaptor Molecule 2 (TICAM2) (C-Term) antibodyTICAM2 Reactivity: Human, Mouse, Rat WB, IHC (p), EIA Host: Rabbit Polyclonal unconjugated
anti-Toll-Like Receptor Adaptor Molecule 2 (TICAM2) (AA 12-41), (N-Term) antibodyTICAM2 Reactivity: Human WB Host: Rabbit Polyclonal RB34146 unconjugated
anti-Toll-Like Receptor Adaptor Molecule 2 (TICAM2) (AA 1-235) antibodyTICAM2 Reactivity: Human WB Host: Mouse Polyclonal unconjugated
anti-Toll-Like Receptor Adaptor Molecule 2 (TICAM2) (AA 34-241) antibodyTICAM2 Reactivity: Human WB, IHC, ICC Host: Rabbit Polyclonal unconjugated
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Neat serum containing 0.02 % sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
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Short Term Storage: +4°C
Long Term Storage: -20°C
Stable for at least 1 year after receipt when stored at -20°C. - Expiry Date
- 12 months
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: "Interferon regulatory factor 3-dependent responses to lipopolysaccharide are selectively blunted in cord blood cells." in: Blood, Vol. 109, Issue 7, pp. 2887-93, (2007) (PubMed).
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: "Interferon regulatory factor 3-dependent responses to lipopolysaccharide are selectively blunted in cord blood cells." in: Blood, Vol. 109, Issue 7, pp. 2887-93, (2007) (PubMed).
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- Target
- TICAM2 (Toll-Like Receptor Adaptor Molecule 2 (TICAM2))
- Alternative Name
- TRAM (TICAM2 Products)
- Synonyms
- MyD88-4 antibody, TICAM-2 antibody, TIRAP3 antibody, TIRP antibody, TRAM antibody, B430113A10 antibody, Tirp antibody, Trif antibody, toll like receptor adaptor molecule 2 antibody, toll-like receptor adaptor molecule 2 antibody, TICAM2 antibody, Ticam2 antibody
- Background
- TRAM functions in LPS-TLR4 signaling to regulate the MYD88-independent pathway during the innate immune response to LPS. It is also involved in IL-1-triggered NF-kappaB activation, functioning upstream of IRAK1, IRAK2, TRAF6 and IKBKB. TRAM physically bridges TLR4 and TICAM-1 and functionally transmits LPS-TRL4 signal to TICAM-1. It is expressed in spleen, prostate, testis, uterus, small intestine, colon, peripheral blood leukocytes, heart, placenta, lung, liver, skeletal muscle and pancreas.
- UniProt
- Q86XR7
- Pathways
- TLR Signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades
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