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IDO1 antibody
IDO1
Reactivity: Human
WB, ELISA, IHC
Host: Mouse
Monoclonal
ID 177
unconjugated
Product Details anti-IDO1 Antibody
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Target
See all IDO1 Antibodies
IDO1
(Indoleamine 2,3-Dioxygenase 1 (IDO1))
Reactivity
All reactivities for IDO1 antibodies
Human
Host
All hosts for IDO1 antibodies
Mouse
Clonality
All clonalities for IDO1 antibodies
Monoclonal
Conjugate
All conjugates for IDO1 antibodies
This IDO1 antibody is un-conjugated
Application
All applications for IDO1 antibodies
Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
Specificity
Recognizes human IDO. Detects a band of ~45 kDa by Western blot.
Cross-Reactivity
Human
Cross-Reactivity (Details)
Other species not tested.
Sterility
0.2 μm filtered
Immunogen
Recombinant human IDO.
Clone
ID 177
Isotype
IgG1
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Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Format
Liquid
Concentration
Lot specific
Buffer
0.2μm-filtered solution in PBS, pH 7.4. Contains no preservatives.
Preservative
Without preservative
Storage
4 °C,-20 °C
Storage Comment
Short Term Storage: +4°C Long Term Storage: -20°C Stable for at least 1 year after receipt when stored at -20°C.
Expiry Date
12 months
Target Details for IDO1
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Target
IDO1
(Indoleamine 2,3-Dioxygenase 1 (IDO1))
Alternative Name
IDO (IDO1 Products )
Synonyms
INDO antibody, ido antibody, indo antibody, IDO antibody, cd107b antibody, IDO1 antibody, IDO-1 antibody, Ido antibody, Indo antibody, indoleamine 2,3-dioxygenase 1 antibody, indoleamine 2,3-dioxygenase 1 L homeolog antibody, indoleamine 2,3-dioxygenase 1-like antibody, IDO1 antibody, ido1.L antibody, ido1 antibody, Ido1 antibody, LOC100050681 antibody
Background
IDO catalyzes the first and rate-limiting step in the main pathway of human tryptophan catabolism, the kynurenine pathway. Proinflammatory mediators, such as endotoxin and IFN-gamma induce the expression of IDO in several tissues. IDO-dependent suppression of T-cell responses might function as natural immunoregulatory mechanism. Physiological IDO activity has been implicated in T-cell tolerance to tumors, dysfunctional selftolerance in non-obese diabetic (NOD) mice, and as a protective negative regulator in autoimmune disorders.
UniProt
P14902
Pathways
Activated T Cell Proliferation
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