IL-33 antibody
(1 reference)-
- Target See all IL-33 (IL33) Antibodies
- IL-33 (IL33) (Interleukin 33 (IL33))
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This IL-33 antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP), Functional Studies (Func)
- Specificity
- Recognizes human IL-33.
- Cross-Reactivity
- Human
- No Cross-Reactivity
- Mouse (Murine)
- Cross-Reactivity (Details)
- Does not cross-react with mouse IL-33.
- Sterility
- 0.2 μm filtered
- Immunogen
- Recombinant human IL-33.
- Clone
- IL33305B
- Isotype
- IgG2a
- Top Product
- Discover our top product IL33 Primary Antibody
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anti-Interleukin 33 (IL33) (AA 112-270) antibody
IL33 Reactivity: Human WB, IHC, IP, ICC Host: Mouse Monoclonal C11 unconjugated
anti-Interleukin 33 (IL33) antibodyIL33 Reactivity: Human WB, ELISA, IHC, IP, Func Host: Mouse Monoclonal IL33305B unconjugated
anti-Interleukin 33 (IL33) (AA 110-261) antibodyIL33 Reactivity: Rat WB, IHC, IP, ICC Host: Mouse Monoclonal 2# unconjugated
anti-Interleukin 33 (IL33) (AA 185-264) antibodyIL33 Reactivity: Mouse, Rat ELISA, FACS, IHC (p), IF (p), IF (cc), IHC (fro) Host: Rabbit Polyclonal unconjugated
anti-Interleukin 33 (IL33) (AA 171-269) antibodyIL33 Reactivity: Human WB, ELISA Host: Mouse Monoclonal 2D8 unconjugated
anti-Interleukin 33 (IL33) (AA 102-264) antibodyIL33 Reactivity: Mouse, Rat WB, ELISA, IHC Host: Rabbit Polyclonal unconjugated
anti-Interleukin 33 (IL33) antibodyIL33 Reactivity: Human WB, IHC (p), EIA, Func Host: Rabbit Polyclonal unconjugated
anti-Interleukin 33 (IL33) antibody (Biotin)IL33 Reactivity: Human WB, EIA Host: Rabbit Polyclonal Biotin
anti-Interleukin 33 (IL33) antibodyIL33 Reactivity: Human WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated
anti-Interleukin 33 (IL33) (AA 123-276) antibodyIL33 Reactivity: Human ELISA, IHC, IF Host: Rabbit Polyclonal unconjugated
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- 0.2μm-filtered solution in PBS, pH 7.4. Contains no preservatives.
- Preservative
- Without preservative
- Storage
- 4 °C,-20 °C
- Storage Comment
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Short Term Storage: +4°C
Long Term Storage: -20°C
Stable for at least 1 year after receipt when stored at -20°C. - Expiry Date
- 12 months
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: "Cigarette smoke alters IL-33 expression and release in airway epithelial cells." in: Biochimica et biophysica acta, Vol. 1842, Issue 9, pp. 1630-7, (2014) (PubMed).
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: "Cigarette smoke alters IL-33 expression and release in airway epithelial cells." in: Biochimica et biophysica acta, Vol. 1842, Issue 9, pp. 1630-7, (2014) (PubMed).
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- Target
- IL-33 (IL33) (Interleukin 33 (IL33))
- Alternative Name
- IL-33 (IL33 Products)
- Synonyms
- IL33 antibody, C9orf26 antibody, DVS27 antibody, IL1F11 antibody, NF-HEV antibody, NFEHEV antibody, RP11-575C20.2 antibody, 9230117N10Rik antibody, Il-33 antibody, Il1f11 antibody, RGD1311155 antibody, interleukin 33 antibody, IL33 antibody, Il33 antibody
- Background
- Interleukin-33 (IL-33, HF-NEV, IL-1F11), a member of the IL-1 family of cytokines, is expressed by many cell types following pro-inflammatory stimulation and is thought to be released on cell lysis. The 30 kDa human IL33 is converted by CASP1 to a 18 kDa protein. IL33 binds to and signals through ST2 (IL1R1) and its stimulation recruits MYD88, IRAK, IRAK4, and TRAF6, followed by phosphorylation of ERK1 (MAPK3)/ERK2 (MAPK1), p38(MAPK14), and JNK. The ability of IL-33 to target numerous immune cell types, like Th2-like cells, mast cells, and B1 cells, and to induce cytokine and chemokine production underlines its potential in influencing the outcome of a wide range of diseases, such as arthritis, asthma, atopic allergy & anaphylaxis, cardiovascular disease/atherosclerosis, nervous system diseases, and sepsis.
- UniProt
- O95760
- Pathways
- Production of Molecular Mediator of Immune Response
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