Granulin antibody

Catalog No. ABIN1169131

Product Details anti-Granulin Antibody

Target: Granulin (GRN)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Granulin antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Specificity: Recognizes human granulin C. Detects a band of ~12 kDa by Western blot.

Cross-Reactivity: Human

Cross-Reactivity (Details): Cross-reacts with human progranulin.

Sterility: 0.2 μm filtered

Immunogen: Recombinant human granulin C.

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: 0.2μm-filtered solution in PBS, pH 7.4. Contains no preservatives.

Preservative: Without preservative

Storage: 4 °C,-20 °C

Storage Comment: Short Term Storage: +4°C
Long Term Storage: -20°C
Stable for at least 6 months after receipt when stored at -20°C.

Expiry Date: 6 months

References for anti-Granulin antibody (ABIN1169131)

Holler, Taylor, Deng, Kukar: "Intracellular Proteolysis of Progranulin Generates Stable, Lysosomal Granulins that Are Haploinsufficient in Patients with Frontotemporal Dementia Caused by GRN Mutations." in: eNeuro, Vol. 4, Issue 4, (2018) (PubMed).

Target Details for Granulin

Target: Granulin (GRN)

Abstract: GRN Products

Synonyms: GRN antibody, grn antibody, wu:fb11g12 antibody, wu:fj18f05 antibody, MGC53354 antibody, DKFZp459H066 antibody, CLN11 antibody, GEP antibody, GP88 antibody, PCDGF antibody, PEPI antibody, PGRN antibody, epithelin antibody, acrogranin antibody, granulin precursor antibody, granulin a antibody, Granulins antibody, granulin L homeolog antibody, granulin antibody, GRN antibody, grna antibody, grn antibody, grn.L antibody, granulin antibody, ORF1 granulin antibody, Grn antibody

Background: Granulins have possible cytokine-like activity. They are important in normal development, inflammation, wound repair, and tumorigenesis.

UniProt: P28799