×
For best experience we recommend to activate Javascript in your browser.
LAG3 antibody
LAG3
Reactivity: Human, Monkey
WB, ELISA, IHC, ICC, IP, Func
Host: Mouse
Monoclonal
1-10E-04
unconjugated
Product Details anti-LAG3 Antibody
(hide)
Target
See all LAG3 Antibodies
LAG3
(Lymphocyte-Activation Gene 3 (LAG3))
Reactivity
All reactivities for LAG3 antibodies
Human, Monkey
Host
All hosts for LAG3 antibodies
Mouse
Clonality
All clonalities for LAG3 antibodies
Monoclonal
Conjugate
All conjugates for LAG3 antibodies
This LAG3 antibody is un-conjugated
Application
All applications for LAG3 antibodies
Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunoprecipitation (IP), Functional Studies (Func)
Specificity
Recognizes human and monkey LAG-3.
Cross-Reactivity
Human, Monkey
Purification
Purified from concentrated hybridoma tissue culture supernatant.
Purity
>95 % (SDS-PAGE)
Endotoxin Level
<0.001EU/μg purified protein or <1EU/mg purified protein (LAL test, Lonza).
Immunogen
Recombinant human LAG-3.
Clone
1-10E-04
Isotype
IgG1
Top Product
Discover our top product LAG3 Primary Antibody
Alternatives
(show)
Application Details
(hide)
Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
(hide)
Format
Liquid
Concentration
Lot specific
Buffer
In PBS.
Preservative
Without preservative
Storage
4 °C,-20 °C
Storage Comment
Short Term Storage: +4°C Long Term Storage: -20°C Stable for at least 1 year after receipt when stored at -20°C.
Expiry Date
12 months
Target Details for LAG3
(hide)
Target
LAG3
(Lymphocyte-Activation Gene 3 (LAG3))
Alternative Name
LAG-3 (LAG3 Products )
Synonyms
CD223 antibody, LAG-3 antibody, Ly66 antibody, lymphocyte activating 3 antibody, lymphocyte-activation gene 3 antibody, LAG3 antibody, Lag3 antibody
Background
Lymphocyte activation gene 3 (LAG-3, CD223) plays an important role in negatively regulating T cell proliferation, function and homeostasis. It is required for maximal natural and induced regulatory T cell (Treg) function. LAG-3 is closely related to the T cell co-receptor CD4 and binds to MHC class II molecules but with a significantly higher affinity than CD4.
UniProt
P18627
Pathways
Regulation of Leukocyte Mediated Immunity , Positive Regulation of Immune Effector Process , Cancer Immune Checkpoints
Recently viewed
(hide)