SIRT2 antibody
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- Target See all SIRT2 Antibodies
- SIRT2 (Sirtuin 2 (SIRT2))
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This SIRT2 antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA
- Specificity
- Recognizes human sirtuin 2. Detects a band of ~45 kDa by Western blot.
- Cross-Reactivity
- Human
- Sterility
- 0.2 μm filtered
- Immunogen
- Recombinant human sirtuin 2.
- Top Product
- Discover our top product SIRT2 Primary Antibody
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- 0.2μm-filtered solution in PBS, pH 7.4. Contains no preservatives.
- Preservative
- Without preservative
- Storage
- 4 °C,-20 °C
- Storage Comment
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Short Term Storage: +4°C
Long Term Storage: -20°C
Stable for at least 6 months after receipt when stored at -20°C. - Expiry Date
- 6 months
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- Target
- SIRT2 (Sirtuin 2 (SIRT2))
- Alternative Name
- Sirtuin 2 (SIRT2 Products)
- Background
- Sirtuin-2 is a NAD-dependent protein deacetylase, which deacetylates the 'Lys-40' of a-tubulin. It is involved in the control of mitotic exit in the cell cycle. Furthermore, a variety of age-associated diseases such as type 2 diabetes, obesity, osteoporosis, and Alzheimer's disease are associated with sirtuins. Selective inhibition of Sirtuin-2 achieves neuroprotection and identifies Sirtuin-2 to be a potential therapeutic avenue in Huntington's and Parkinson's disease.
- UniProt
- Q8IXJ6
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