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CRNN antibody (AA 259-274)

CRNN Reactivity: Human WB, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN1169072
  • Target See all CRNN Antibodies
    CRNN (Cornulin (CRNN))
    Binding Specificity
    • 6
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 259-274
    Reactivity
    • 13
    • 2
    • 2
    • 2
    • 1
    Human
    Host
    • 13
    Rabbit
    Clonality
    • 13
    Polyclonal
    Conjugate
    • 9
    • 2
    • 1
    • 1
    This CRNN antibody is un-conjugated
    Application
    • 8
    • 8
    • 3
    Western Blotting (WB), Immunohistochemistry (IHC)
    Specificity
    Recognizes human cornulin. Detects a band of ~70 kDa by Western blot.
    Cross-Reactivity
    Human
    Immunogen
    Synthetic peptide corresponding to aa 259-274 (E259ATNDQNRGTETHGQG274) of human cornulin.
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    In PBS containing 1 % BSA and 0.01 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Short Term Storage: +4°C
    Long Term Storage: -20°C
    Stable for at least 1 year after receipt when stored at -20°C.
    Expiry Date
    12 months
  • Contzler, Favre, Huber, Hohl: "Cornulin, a new member of the "fused gene" family, is expressed during epidermal differentiation." in: The Journal of investigative dermatology, Vol. 124, Issue 5, pp. 990-7, (2005) (PubMed).

  • Target
    CRNN (Cornulin (CRNN))
    Alternative Name
    Cornulin (CRNN Products)
    Synonyms
    C1orf10 antibody, DRC1 antibody, PDRC1 antibody, SEP53 antibody, RGD1311778 antibody, Gm1015 antibody, cornulin antibody, CRNN antibody, Crnn antibody, LOC100359146 antibody
    Background
    Cornulin is a survival factor that participates in the clonogenicity of squamous esophageal epithelium cell lines. It attenuates deoxycholic acid (DCA)-induced apoptotic cell death and the release of calcium. In overexpressed oral squamous carcinoma cell lines, cornulin negatively regulates cell proliferation by the induction of G1 arrest.
    UniProt
    Q9UBG3
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