Netrin 4 antibody (full length)

Catalog No. ABIN1169041

Product Details anti-Netrin 4 Antibody

Target: Netrin 4 (NTN4)

Binding Specificity: full length

Reactivity: Human, Mouse

Host: Mouse

Clonality: Monoclonal

Conjugate: This Netrin 4 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Specificity: Recognizes human and mouse Netrin-4

Cross-Reactivity: Human, Mouse (Murine)

Purification: Purified from concentrated hybridoma tissue culture supernatant.

Purity: >95 % (SDS-PAGE)

Immunogen: Netrin-4 (human) (Full-length)

Clone: Nely-1

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: In PBS containing 10 % glycerol and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Short Term Storage: +4°C
Long Term Storage: -20°C
Stable for at least 1 year after receipt when stored at -20°C.

Expiry Date: 12 months

Target Details for Netrin 4

Target: Netrin 4 (NTN4)

Alternative Name: Netrin-4 (NTN4 Products)

Synonyms: Netrin-4 antibody, PRO3091 antibody, RGD1565947 antibody, netrin 4 antibody, netrin-4 antibody, NTN4 antibody, ntn4 antibody, Ntn4 antibody, LOC100541214 antibody

Background: Netrin-4 is a 628 amino acid laminin-related secreted protein that promotes neurite elongation at low concentrations but inhibits neurite extension at high concentrations. Recent evidence suggest that Netrin family members act as regulators of both neuronal and vascular growth and are implicated in controling epithelial cell branching morphogenesis in the pancreas, breast and lung. Netrin-4 inhibits proliferation of a variety of human tumor cells. Netrin-4 also induces proliferation, migration, adhesion, tube formation and survival of human lymphatic endothelial cells and seems to function as a lymphangiogenic factor contributing to tumor dissemination.

UniProt: Q9HB63