BMP2
Reactivity: Human
WB, FACS
Host: Rabbit
Polyclonal
RB33889
unconjugated
Application Notes
ELISA: 1.0 μg/mL). Western Blot: 1 μg/mL, it will detect 20 ng/lane of recombinant human BMP-2/4-1 orBMP-2/4-2 under reducing conditions. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions
For Research Use only
Reconstitution
After reconstitition add preservatives (0.02 % Sodium Azide or 0.03 % Thimerosal).
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Background
BMP2 belongs to the transforming growth factor beta (TGFB) superfamily of secreted growth factors. It is a disulfide linked homodimer and induces bone and cartilage formation. In addition to its osteogenic activity, BMP2 plays an important role in cardiac morphogenesis and is expressed in a variety of tissues including lung, spleen, brain, liver, prostate ovary and small intestine. The functional form of BMP2 is a 26 kDa protein composed of two identical 114 amino acid polypeptide chains linked by a single disulfide bond. BMPs control fundamental events in early embryonic development, organogenesis and adult tissue homeostasis.Synonyms: BMP-2, BMP-2A, Bone morphogenetic protein 2