CST3 antibody
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- Target See all CST3 Antibodies
- CST3 (Cystatin C (CST3))
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This CST3 antibody is un-conjugated
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Application
- Western Blotting (WB), Enzyme Immunoassay (EIA)
- Specificity
- The antibody was raised in rabbits by immunization with the Cystatin C.
- Purification
- Immunoaffinity chromatography
- Immunogen
- Cystatin C from human urine
- Top Product
- Discover our top product CST3 Primary Antibody
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- Application Notes
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ELISA. Western Blot.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
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- Reconstitution
- Restore with 0.1 mL of deionized water
- Concentration
- 1.0 mg/mL
- Buffer
- 0.05 M phosphate buffer, 0.1 M NaCl, pH 7.2. AZIDE FREE
- Preservative
- Azide free
- Handling Advice
- Avoid repeated freezing and thawing.
- Storage
- -20 °C
- Storage Comment
- Prior to reconstitution store at -70 °C. Following reconstitution store the antibody (in aliquots) at -20 °C for 6 month.
- Expiry Date
- 6 months
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- Target
- CST3 (Cystatin C (CST3))
- Alternative Name
- Cystatin-C (CST3 Products)
- Background
- Cystatin C is a non-glycosilated basic single-chain protein consisting of 120 amino acids with a molecular weight of 13.36 kDa and is characterized by two disulfide bonds in the carboxy-terminal region. It belongs to the cystatins superfamilly which inactivates lysosomal cysteine proteinases, e.g. cathepsin B, H,.K, L and S. Imbalance between Cystatin C and cysteine proteinases is associated with inflammation, renal failure, cancer, Alzheimers disease, multiple sclerosis and hereditary Cystatin C amyloid angiopathy. Its increased level has been found in patients with autoimune diseases, with colorectal tumors and in patients on dyalisis. Serum Cystatin C seems to be better marker of glomerular filtration rate than creatinine. On the other hand, low concentration of Cystatin C presents a risk factor for secondary cardiovascular events.Synonyms: CST3, Cystatin C, Cystatin-3, Gamma-trace, Neuroendocrine basic polypeptide, Post-gamma-globulin
- Gene ID
- 1471
- NCBI Accession
- NP_000090
- UniProt
- P01034
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