Helicobacter Pylori antibody

Catalog No. ABIN115309

Product Details anti-Helicobacter Pylori Antibody

Target: Helicobacter Pylori (H. pylori)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Helicobacter Pylori antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: Purified

Immunogen: Total lysate of H. pylori

Application Details

Application Notes: Immunohistochemistry on Paraffin Embedded Sections: Use a dilution of 1/50-1/100 in anABC method (30 minutes at RT). Formalin fixed paraffin embedded tissue sections require high temperature antigenunmasking with 10 mM citrate buffer, pH 6.0 prior to immunostaining. Recommended Positive Control: infected stomach.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for Helicobacter Pylori

Target: Helicobacter Pylori (H. pylori)

Alternative Name: Helicobacter Pylori (H. pylori Products)

Target Type: Virus

Background: The spiral shaped bacterium Helicobacter pylori is strongly associated with inflammation of the stomach and is also implicated in the development of gastric malignancy. H. pylori is known to cause peptic ulcers and chronic gastritis in human. It is associated with duodenal ulcers and may be involved in development of adenocarcimona and low-grade lymphoma of mucosa associated lymphoid tissue in the stomach. More recently this bacterium has also been implicated with a number of vascular disorders including heart disease. It is not clear how H. pylori is transmitted or why some patients become symptomatic while others do not. The bacteria are most likely spread from person to person through fecal-to-oral or oral-to-oral routes. Possible environmental reservoirs include contaminated water sources. Serological tests that measure specific H. pylori IgG antibodies can determine if a person has been infected although these methods do have drawbacks and limitations.Synonyms: H. pylori