Reactive with natural and recombinant human MCP-3. Does not show any cross reaction with other Human Cytokines or growth factors tested such as IL1 beta, IL-8, MCAF, SAA and EGF.
CCL7
Reactivity: Rat
IHC
Host: Rabbit
Polyclonal
unconjugated
Application Notes
ELISA. Western Blot: An antibody concentration of 0.5-2 μg/mL will allow visualization of 0.1 μg/lane of Human MCP-3. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions
For Research Use only
Reconstitution
Restore with double distillated water to adjust the final concentration to 1.00 mg/mL
Buffer
0.01 M PBS, pH 7.2 without preservatives.
Preservative
Without preservative
Handling Advice
This product is photosensitive and should be protected from light
MCP3/CCL7 is a secreted chemokine which attracts macrophages during inflammation and metastasis. It is a member of the C-C subfamily of chemokines which are characterized by having two adjacent cysteine residues. The protein is an in vivo substrate of matrix metalloproteinase 2, an enzyme which degrades components of the extracellular matrix.Synonyms: C-C motif chemokine 7, CCL-7, MCP-3, Macrophage Chemotactic Protein-3, Monocyte chemoattractant protein 3, Monocyte chemotactic protein 3, NC28, SCYA6, SCYA7, Small-inducible cytokine A7