Creatine Kinase MB antibody

Catalog No. ABIN111813

Product Details anti-Creatine Kinase MB Antibody

Target: Creatine Kinase MB (CKM)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Creatine Kinase MB antibody is un-conjugated

Application: Enzyme Immunoassay (EIA), Radioimmunoassay (RIA)

Purification: Affinity chromatography on Protein A

Immunogen: Highly purified human CK-MB.

Clone: 1F2-1

Isotype: IgG2b

Application Details

Application Notes: ELISA. IRMA.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: PBS containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for Creatine Kinase MB

Target: Creatine Kinase MB (CKM)

Alternative Name: CKMB (CKM Products)

Synonyms: CKMM antibody, M-CK antibody, Ckmm antibody, MCK antibody, creatine kinase, M-type antibody, creatine kinase, muscle antibody, CKM antibody, Ckm antibody

Background: Creatine Kinase MB consists of a dimer of nonidentical chains. With MM being the major form in skeletal muscle and myocardium, MB existing in myocardium, and BB existing in many tissues, especially brain. Creatine Kinase MB reversibly catalyses the transfer of phosphate between ATP and various phosphogens. The creatine kinase isoenzymes play a central role in energy transduction in tissues with large fluctuating energy demands such as skeletal muscle, heart, brain and spermatozoa. Creatine phosphokinase, also known as creatine kinase (CK), is an enzyme expressed by various tissues and cell types. CK catalyses the conversion of creatine and consumes adenosine triphosphate (ATP) to create phosphocreatine and adenosine diphosphate (ADP). In cells, the "cytosolic" CK enzymes consist of two subunits, which can be either B (brain type) or M (muscle type). There are three different isoenzymes: CKMM, CKBB and CKMB.Synonyms: CK-MB, Creatine Kinase MB