PRKDC antibody (Catalytic Subunit)
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- Target See all PRKDC Antibodies
- PRKDC (Protein Kinase, DNA-Activated, Catalytic Polypeptide (PRKDC))
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Binding Specificity
- Catalytic Subunit
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Reactivity
- Mouse
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This PRKDC antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)
- Immunogen
- Recombinant DNA-PKcs protein.
- Clone
- N9
- Isotype
- IgG2a
- Top Product
- Discover our top product PRKDC Primary Antibody
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anti-Protein Kinase, DNA-Activated, Catalytic Polypeptide (PRKDC) antibody
PRKDC Reactivity: Human ELISA, IHC, ICC Host: Mouse Monoclonal 3H6 unconjugated
anti-Protein Kinase, DNA-Activated, Catalytic Polypeptide (PRKDC) (AA 4019-4128) antibodyPRKDC Reactivity: Human ELISA, WB, IF, IHC (p) Host: Mouse Monoclonal 1B9 unconjugated
anti-Protein Kinase, DNA-Activated, Catalytic Polypeptide (PRKDC) antibodyPRKDC Reactivity: Human WB, IHC, IP, ICC Host: Mouse Monoclonal unconjugated
anti-Protein Kinase, DNA-Activated, Catalytic Polypeptide (PRKDC) (C-Term) antibodyPRKDC Reactivity: Human, Mouse ELISA, WB, IHC, IF, ICC Host: Rabbit Polyclonal unconjugated
anti-Protein Kinase, DNA-Activated, Catalytic Polypeptide (PRKDC) (pThr2609) antibodyPRKDC Reactivity: Human ELISA, WB, IP Host: Rabbit Polyclonal unconjugated
anti-Protein Kinase, DNA-Activated, Catalytic Polypeptide (PRKDC) (C-Term) antibodyPRKDC Reactivity: Human ELISA, WB, IHC, IF Host: Rabbit Polyclonal unconjugated
anti-Protein Kinase, DNA-Activated, Catalytic Polypeptide (PRKDC) (AA 3899-4128) antibodyPRKDC Reactivity: Mouse WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated
anti-Protein Kinase, DNA-Activated, Catalytic Polypeptide (PRKDC) (AA 151-300) antibodyPRKDC Reactivity: Human, Rat ELISA, WB, IHC (p) Host: Rabbit Polyclonal unconjugated
anti-Protein Kinase, DNA-Activated, Catalytic Polypeptide (PRKDC) (C-Term) antibodyPRKDC Reactivity: Human, Mouse ELISA, WB, IHC, IF Host: Rabbit Polyclonal unconjugated
anti-Protein Kinase, DNA-Activated, Catalytic Polypeptide (PRKDC) (pThr2647) antibodyPRKDC Reactivity: Human ELISA, WB, IHC, IF, ICC Host: Rabbit Polyclonal unconjugated
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- Application Notes
- WB (1:1000), IHC-P (1:200), ICC (1:100). Other applications have not been tested. The optimal dilutions should be determined by end user.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- TBS (pH7.4), 0.5% BSA, 40% Glycerol and 0.05% Sodium Azide.
- Preservative
- Sodium azide, Thimerosal (Merthiolate)
- Storage
- 4 °C/-20 °C
- Storage Comment
- Store at 4 °C after thawing (1 week). Aliquot and store at -20 °C for long term (at least one year). Avoid repeated freeze and thaw cycles.
- Expiry Date
- 12 months
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- Target
- PRKDC (Protein Kinase, DNA-Activated, Catalytic Polypeptide (PRKDC))
- Abstract
- PRKDC Products
- Background
- DNA-dependent protein kinase, catalytic subunit, also known as DNA-PKcs, is an enzyme that belongs to the phosphatidylinositol 3-kinase-related kinase protein family. Anderson and Lees-Miller (1992) noted that DNA-PK had been shown in vitro to phosphorylate several transcription factors, suggesting that it functions in cell homeostasis by modulating transcription. It acts as a molecular sensor for DNA damage, and it may also act as a scaffold protein to aid the localization of DNA repair proteins to the site of damage.
- Pathways
- DNA Damage Repair, Production of Molecular Mediator of Immune Response
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