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ZNF496 antibody (Middle Region)
ZNF496
Reactivity: Mouse, Human, Cow, Dog
WB
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-ZNF496 Antibody
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Target
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ZNF496
(Zinc Finger Protein 496 (ZNF496))
Binding Specificity
All epitopes for ZNF496 antibodies
Middle Region
Reactivity
All reactivities for ZNF496 antibodies
Mouse, Human, Cow, Dog
Host
All hosts for ZNF496 antibodies
Rabbit
Clonality
All clonalities for ZNF496 antibodies
Polyclonal
Conjugate
All conjugates for ZNF496 antibodies
This ZNF496 antibody is un-conjugated
Application
All applications for ZNF496 antibodies
Western Blotting (WB)
Sequence
QEKPHECSVC GELFSDSEDL DGHLESHEAQ KPYRCGACGK SFRLNSHLLS
Cross-Reactivity (Details)
Species reactivity (expected):Mouse, Dog, BovineSpecies reactivity (tested):Human
Purification
Purified on peptide immunoaffinity column
Immunogen
Synthetic peptide directed towards the middle region of human ZNF496
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Discover our top product ZNF496 Primary Antibody
Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Reconstitution
Add 50 μL of distilled water
Handling Advice
Avoid repeated freezing and thawing.
Storage
-20 °C
Storage Comment
Store the lyophised antibody at -20 °C for up to one year. Store reconstitued antibody undiluted for one month or in aliquots at -20 °C long term.
Expiry Date
12 months
Target Details for ZNF496
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Target
ZNF496
(Zinc Finger Protein 496 (ZNF496))
Alternative Name
ZNF496 (ZNF496 Products )
Synonyms
Zkscan17 antibody, Znf496 antibody, ZNF496 antibody, NIZP1 antibody, ZFP496 antibody, ZKSCAN17 antibody, ZSCAN49 antibody, BC040205 antibody, D130067D09 antibody, Nizp1 antibody, Zfp496 antibody, zinc finger protein 496 antibody, zinc finger with KRAB and SCAN domains 17 antibody, Zfp496 antibody, ZNF496 antibody, Zkscan17 antibody
Background
ZNF496 contains a SCAN box, a KRAB-A domain, and four consensus C2H2-type zinc fingers preceded by a unique finger derivative, referred to herein as the C2HR motif. The C2HR motif functions to mediate protein-protein interaction with the cysteine-rich (C5HCH) domain of NSD1 in a Zn(II)-dependent fashion, and when tethered to RNA polymerase II promoters, represses transcription in an NSD1-dependent manner. ZNF496 contains a novel type of zinc finger motif that functions as a docking site for NSD1 and is more than just a degenerate evolutionary remnant of a C2H2 motif.Synonyms: ZKSCAN17, Zinc finger protein 496, Zinc finger protein with KRAB and SCAN domains 17
Gene ID
84838
NCBI Accession
NP_116141
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