TGM1 antibody

Catalog No. ABIN1109301

Product Details anti-TGM1 Antibody

Target: TGM1 (Transglutaminase 1, Keratinocyte (TGM1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TGM1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro)), Enzyme Immunoassay (EIA)

Specificity: This antibody is specific to keratinocyte Transglutaminase 1.

Cross-Reactivity (Details): Species reactivity (tested):Human.

Purification: Affinity Chromatography on Protein A

Immunogen: A 15 residue synthetic peptide derived from specific domain of Transglutaminase-1 protein.

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Reconstitution: Restore in distilled water.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Prior to reconstitution store the antibody at -20 °C. Store reconstituted antibody at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for TGM1

Target: TGM1 (Transglutaminase 1, Keratinocyte (TGM1))

Alternative Name: Transglutaminase-1 (TGM1) (TGM1 Products)

Synonyms: TGM1 antibody, ARCI1 antibody, ICR2 antibody, KTG antibody, LI antibody, LI1 antibody, TGASE antibody, TGK antibody, 2310004J08Rik antibody, Tgase1 antibody, transglutaminase 1 antibody, transglutaminase 1, K polypeptide antibody, Tgm1 antibody, TGM1 antibody

Background: Tissue transglutaminase is a calcium activated enzyme which catalyzes the cross linking of proteins and the conjugation of polyamines to proteins. The identification of transglutaminase as the main antigen of endomysium antibodies allows a new diagnostic approach to celiac disease (CD). CD, a genetic, immunologically mediated small bowel enteropathy that causes malabsorption, is one of the more common disorders in Western countries.Synonyms: Epidermal TGase, KTG, Protein-glutamine gamma-glutamyltransferase K, TGase K, Transglutaminase K

Molecular Weight: 90 kDa

Gene ID: 7051

NCBI Accession: NP_000350