Spectrin beta Chain, Erythrocyte (SPTB) antibody
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- Target See all Spectrin beta Chain, Erythrocyte (SPTB) Antibodies
- Spectrin beta Chain, Erythrocyte (SPTB)
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- Un-conjugated
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Application
- Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP)
- Specificity
- The antibody clone AF10 is specific to the 240 kDa Erythroid alpha-Spectrin. This antibody is suitable for Various immunochemical reactions to detect Erythroid Spectrins, Identification of Erythroid leukemias (Ref.1).
- Cross-Reactivity (Details)
- Species reactivity (tested):Human.
- Purification
- Purified
- Immunogen
- Ghost proteins of Human red blood cells. Hybridoma produced by fusion between myeloma cells and Balb/c spleen cells.
- Clone
- DB2
- Isotype
- IgG1
- Top Product
- Discover our top product SPTB Primary Antibody
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Concentration
- 0.1 mg/mL
- Buffer
- PBS, 0.09 % Sodium Azide, 1.0 % BSA
- Preservative
- Sodium azide
- Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C
- Storage Comment
- Store the antibody undiluted at 2-8 °C.
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- Target
- Spectrin beta Chain, Erythrocyte (SPTB)
- Alternative Name
- Spectrin beta Chain (Erythrocyte) / SPTB (SPTB Products)
- Synonyms
- AI842465 antibody, D330027P03Rik antibody, Gm1301 antibody, Spnb-1 antibody, Spnb1 antibody, ja antibody, jaundiced antibody, mKIAA4219 antibody, EL3 antibody, HS2 antibody, HSPTB1 antibody, SPH2 antibody, spectrin beta, erythrocytic antibody, spectrin, beta, erythrocytic antibody, SPTB antibody, Sptb antibody
- Background
- Erythroid spectrins, some other proteins of erythroid cytoskeleton, and the transmembrane protein band 3 are highly specific for erythrocytes and their progenitors. They are more reliable markers for erythroid differentiation than Glycophorin A, the commonly used marker for erythroid differentiation, because Glycophorin A is expressed also in many cell lines otherwise exhibiting mainly megakaryotic charasteristics.Synonyms: Beta-I spectrin, SPTB1
- Gene ID
- 6710
- NCBI Accession
- NP_000338
- UniProt
- P11277
- Pathways
- Regulation of Actin Filament Polymerization
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