Polymyxin B antibody
Reactivity: Bacillus polymyxa
WB, EIA
Host: Mouse
Monoclonal
45
unconjugated
-
- Target See all Polymyxin B products
- Polymyxin B
- Reactivity
- Bacillus polymyxa
-
Host
- Mouse
-
Clonality
- Monoclonal
-
Conjugate
- This Polymyxin B antibody is un-conjugated
- Application
- Western Blotting (WB), Enzyme Immunoassay (EIA)
- Endotoxin Level
- Low Endotoxin
- Clone
- 45
- Isotype
- IgM
-
-
- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
-
- Concentration
- > 0.2 mg/mL
- Buffer
- 0.02 % Sodium Azide
- Preservative
- Sodium azide
- Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freezing and thawing.
- Storage
- 4 °C/-20 °C
- Storage Comment
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
-
- Target
- Polymyxin B
- Abstract
- Polymyxin B Products
- Background
- The peptide antibiotic Polymyxin B (PMB) binds to bacterial endotoxin (lipopolysaccharide, LPS). The interaction of PMB with LPS involves ionic forces between amino groups in PMB and negatively charged phosphate and carboxyl groups in the lipid A-Kdo region. PMB has relevance for endotoxin research in at least two ways: first, PMB reacts with LPS of many species regardless of varied serospecificity, and thus it can be used as a general probe for measuring or detecting LPS or lipid A. Second, binding of PMB to LPS may result in neutralization of the detrimental effects of LPS either in vitro or in vivo.
-
You are here:
