Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@antibodies-online.com

PMVK antibody (Middle Region)

PMVK Reactivity: Human, Mouse, Rat WB, IHC (p), IF Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN1108679
  • Target See all PMVK Antibodies
    PMVK (Phosphomevalonate Kinase (PMVK))
    Binding Specificity
    • 15
    • 6
    • 2
    • 2
    • 2
    • 1
    • 1
    Middle Region
    Reactivity
    Human, Mouse, Rat
    Host
    • 29
    • 8
    Rabbit
    Clonality
    • 30
    • 6
    Polyclonal
    Conjugate
    • 19
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PMVK antibody is un-conjugated
    Application
    • 33
    • 13
    • 13
    • 7
    • 7
    • 5
    • 5
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)
    Specificity
    This antibody detects PMVK (mid region). No cross reactivity with other proteins.
    Cross-Reactivity (Details)
    Species reactivity (tested):Human, Mouse, Rat.
    Purification
    Immunoaffinity Chromatography
    Immunogen
    Synthetic peptide corresponding to a sequence mapping at the middle region of Human PMVK .Remarks: Sequence is different from the related Mouse and Rat sequence by single amino acid.
    Isotype
    IgG
    Top Product
    Discover our top product PMVK Primary Antibody
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Reconstitution
    0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    Buffer
    0.2 mg Na2HPO4, 0.9 mg NaCl, 0.05 mg Thimerosal, 0.05 mg Sodium Azide, 5 mg BSA
    Preservative
    Thimerosal (Merthiolate)
    Precaution of Use
    This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Target
    PMVK (Phosphomevalonate Kinase (PMVK))
    Alternative Name
    PMVK (PMVK Products)
    Synonyms
    MPK_Bm antibody, F5M6.9 antibody, F5M6_9 antibody, zgc:162701 antibody, HUMPMKI antibody, PMK antibody, PMKA antibody, PMKASE antibody, 1110011E12Rik antibody, 2900002L22Rik antibody, AV001327 antibody, phosphomevalonate kinase antibody, GHMP kinase family protein antibody, PMVK antibody, Mpk antibody, AT1G31910 antibody, CpipJ_CPIJ015413 antibody, Bm1_05275 antibody, pmvk antibody, LOAG_11811 antibody, Tsp_06629 antibody, LOC100282968 antibody, Pmvk antibody
    Background
    PMVK (phosphomevalonate kinase) is a cytosolic enzyme that catalyzes the conversion of mevalonate-5-phosphate to mevalonate-5-diphosphate. It is mapped to chromosome 1p13-1q22-23 and spans more than 8.4 kb in the human genome. PMVK is a peroxisomal protein which requires the C-terminal peroxisomal targeting signal, Ser-Arg-Leu, for localization to the organelle. It was expressed highly in heart, liver, skeletal muscle, kidney and pancreas and slightly lower in brain, placenta, and lung. And PMKase gene expression is subject to regulation by sterol at the level of transcription. It is a single copy gene covering less than 15 kb in the human genome. The human PMKase amino acid sequence contains a consensus peroxisomal targeting sequence (PTS-1), Ser-Arg-Leu, at the C terminus of the protein.Synonyms: HUMPMKI, PMKI, PMKase, Phosphomevalonate kinase
    Gene ID
    10654
    NCBI Accession
    NP_006547
    UniProt
    Q15126
You are here:
Support